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MICROBiome-based biomarkers to PREDICT decompensation of liver cirrhosis and treatment response

Project description

Identification of microbiome-based biomarkers for end-stage liver disease

The end stage of liver disease is decompensated cirrhosis and progression towards acute-on-chronic liver failure (ACLF), which presents with systemic inflammation and organ failure and has a dismal prognosis. Emerging evidence indicates that the gut microbiome is implicated in liver cirrhosis, but the underlying mechanism remains to be elucidated. MICROB-PREDICT is a programme of excellence funded by the EU that aims to investigate the role of the microbiome in the gut–liver interaction. Researchers will also identify microbiome-based biomarkers associated with end-stage liver disease and generate data from large patient cohorts. Collectively, this information will enable accurate patient stratification and pave the way for personalised therapies.

Call for proposal

H2020-SC1-2018-Single-Stage-RTD
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Coordinator

EUROPEAN FOUNDATION FOR THE STUDY OF CHRONIC LIVER FAILURE (EF-CLIF)
Address
Travessera De Gracia 11, 7Th Floor
08021 Barcelona
Spain
Activity type
Research Organisations
EU contribution
€ 2 273 400

Participants (21)

DEBRECENI EGYETEM
Hungary
EU contribution
€ 347 000
Address
Egyetem Ter 1
4032 Debrecen
Activity type
Higher or Secondary Education Establishments
REGION SYDDANMARK
Denmark
EU contribution
€ 800 000
Address
Damhaven 12
7100 Vejle
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
KOBENHAVNS UNIVERSITET
Denmark
EU contribution
€ 1 246 100
Address
Norregade 10
1165 Kobenhavn
Activity type
Higher or Secondary Education Establishments
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 2 021 900
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
France
EU contribution
€ 648 000
Address
Rue Leblanc 25
75015 Paris 15
Activity type
Research Organisations
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany
EU contribution
€ 996 000
Address
Hofgartenstrasse 8
80539 Munchen
Activity type
Research Organisations
VAIOMER
France
EU contribution
€ 484 000
Address
516 Rue Pierre Et Marie Curie Prologue Biotech
31670 Labege
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
France
EU contribution
€ 620 000
Address
147 Rue De L'universite
75007 Paris Cedex 07
Activity type
Research Organisations
JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
Germany
EU contribution
€ 635 000
Address
Theodor W Adorno Platz 1
60323 Frankfurt Am Main
Activity type
Higher or Secondary Education Establishments
KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium
EU contribution
€ 620 000
Address
Oude Markt 13
3000 Leuven
Activity type
Higher or Secondary Education Establishments
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
EU contribution
€ 500 500
Address
Albinusdreef 2
2333 ZA Leiden
Activity type
Higher or Secondary Education Establishments
UNIVERSITAT DE BARCELONA
Spain
EU contribution
€ 224 000
Address
Gran Via De Les Corts Catalanes 585
08007 Barcelona
Activity type
Higher or Secondary Education Establishments
BIOBYTE SOLUTIONS GMBH
Germany
EU contribution
€ 290 000
Address
Bothestrasse 142
69126 Heidelberg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA
Spain
EU contribution
€ 1 089 400
Address
Campus De La Uab Edifici Q Icn2
08193 Bellaterra (Barcelona)
Activity type
Research Organisations
UNIVERSITY COLLEGE LONDON
United Kingdom
EU contribution
€ 423 500
Address
Gower Street
WC1E 6BT London
Activity type
Higher or Secondary Education Establishments
UNIVERSITETET I OSLO
Norway
EU contribution
€ 150 000
Address
Problemveien 5-7
0313 Oslo
Activity type
Higher or Secondary Education Establishments
EUROPEAN LIVER PATIENTS ASSOCIATION
Belgium
EU contribution
€ 80 000
Address
Rue De La Loi 235/27
1040 Bruxelles
Activity type
Other
Concentris Research Management GmbH
Germany
EU contribution
€ 535 000
Address
Ludwigstr. 4
D-82256 Fürstenfeldbruck
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
KING'S COLLEGE LONDON
United Kingdom
EU contribution
€ 500 000
Address
Strand
WC2R 2LS London
Activity type
Higher or Secondary Education Establishments
FUNDACIO CLINIC PER A LA RECERCA BIOMEDICA
Spain
EU contribution
€ 460 000
Address
Carrer Rossello 149
08036 Barcelona
Activity type
Research Organisations
EUROPEAN ASSOCIATION FOR THE STUDYOF THE LIVER
Switzerland
EU contribution
€ 56 200
Address
Rue Daubin 7
1203 Geneve
Activity type
Other