A pioneering vaccine for diarrhoea may accomplish what predecessors could not
Diarrhoea is typically a non-threatening nuisance in western civilisations but it is a killer in developing countries, particularly for children under five years of age. In cases where children do survive, malnourishment due to poverty is augmented by dehydration and severe undernutrition as a result of infection. This can have long-term effects on physical and cognitive development. SHIGETECVAX is developing a novel oral vaccine against two closely related bacteria that are leading causes of diarrhoea. Based on antigens not targeted in previous vaccines, it is much safer, enabling higher doses. Potentially more effective against both pathogens, this vaccine could save millions of lives.
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Funding SchemeRIA-LS - Research and Innovation action Lump Sum