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Intelligent digital tools for screening of brain connectivity and dementia risk estimation in people affected by mild cognitive impairment.

Objective

More than 10 million Europeans show signs of mild cognitive impairment (MCI), a condition intermediate between normal brain ageing and dementia. The evolution of MCI differs from person to person; some remain stable or return to normal, but 50% progress to dementia within five years. Current practice lacks the necessary screening tools to identify those 50% at risk. The patient’s journey typically takes many years of inefficient clinical follow-ups before a conclusive diagnosis is finally reached.

AI-Mind will radically shorten this journey to 1 week through a digital solution that is able to provide a fast and accurate (>95%) prediction for the individual dementia risk. Our AI-Mind platform service, can be easily integrated into existing clinical practices and contains 2 new artificial-intelligence-based tools. The AI-Mind Connector identifies dysfunctional brain networks. The AI-Mind Predictor assesses demen-tia risk using data from the Connector, advanced cognitive tests, genetic biomarkers and important textual variables. Our aim is to set up a European clinical network that will upload patient data to the AI-Mind European cloud platform.

The consortium comprises excellent researchers in neuroscience and computer science, from 5 clinical cen-tres, who closely collaborate with 3 SMEs contributing unique technologies, an established data govern-ance body, and Alzheimer Europe. Together, they plan to deliver a medical device of class 2b that can reach TRL7 by the end of the project. AI-Mind represents a major step forward in the risk assessment of dementia. Clinicians will promptly advise therapies to delay the onset of disease, and patients will enjoy independent lives for longer. By offering a globally accessible, cheap and precise tool for dementia pre-diction, AI-Mind will improve the health care system and boost innovation by shifting the R&D of phar-maceutical organisations and other companies to preventive diagnostic methods and therapies for dementia.

Call for proposal

H2020-SC1-2020-Single-Stage-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

OSLO UNIVERSITETSSYKEHUS HF
Address
Kirkeveien 166 Tarnbygget
0450 Oslo
Norway
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 3 304 250

Participants (14)

AALTO KORKEAKOULUSAATIO SR
Finland
EU contribution
€ 773 437,50
Address
Otakaari 1
02150 Espoo
Activity type
Higher or Secondary Education Establishments
ACCELOPMENT SCHWEIZ AG
Switzerland
EU contribution
€ 851 250
Address
Seefeldstrasse 198
8008 Zurich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ALZHEIMER EUROPE
Luxembourg
EU contribution
€ 269 375
Address
Rue Dicks 14
1417 Luxembourg
Activity type
Other
BRAINSYMPH AS
Norway
EU contribution
€ 923 350
Address
C/o Ira Hebold Haraldsen Holmenkoll
0784 Olso
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
DNV AS
Norway
EU contribution
€ 758 887,50
Address
Veritasveien 1
1363 Hovik
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ
Finland
EU contribution
€ 1 131 350
Address
Stenbackinkatu 9
00029 Helsinki
Activity type
Research Organisations
SAN RAFFAELE ROMA SRL
Italy
EU contribution
€ 543 437,50
Address
Via Della Pisana 235
00163 Roma Rm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
LURTIS RULES SL
Spain
EU contribution
€ 994 375
Address
Avenida De Carlos V 113 1A
28938 Mostoles
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
NEUROCONNECT SRL
Italy
EU contribution
€ 513 750
Address
Largo Francesco Vito 1
00168 Roma
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
OSLOMET - STORBYUNIVERSITETET
Norway
EU contribution
€ 984 050
Address
Pilestredet 46
0167 Oslo
Activity type
Higher or Secondary Education Establishments
STICHTING KATHOLIEKE UNIVERSITEIT
Netherlands
EU contribution
€ 336 162,50
Address
Houtlaan 4
6525 XZ Nijmegen
Activity type
Higher or Secondary Education Establishments
TALLINN UNIVERSITY
Estonia
EU contribution
€ 443 125
Address
Narva Road 25
10120 Tallinn
Activity type
Higher or Secondary Education Establishments
UNIVERSIDAD COMPLUTENSE DE MADRID
Spain
EU contribution
€ 1 169 125
Address
Avenida De Seneca 2
28040 Madrid
Activity type
Higher or Secondary Education Establishments
UNIVERSITA CATTOLICA DEL SACRO CUORE
Italy
EU contribution
€ 1 002 937,50
Address
Largo Gemelli 1
20123 Milano
Activity type
Higher or Secondary Education Establishments