Project description
From fluorescent protein to protein-polymer matrices and bio-LEDs
Lighting has come a long way over the past decades. Light-emitting diode (LED) lights have largely replaced fluorescent lighting, being up to 80 % more efficient while lasting far longer and being much easier to recycle. However, they rely on rare earth elements as colour down-converting filters. Green fluorescent protein (GFP) found in jellyfish has emerged as a sustainable alternative for bio-LEDs. With the support of the Marie Skłodowska-Curie Actions programme, the BIOS project will augment bio-LEDs’ currently moderate stability and efficiency, through theoretical and computational investigations. Understanding the structural and electronic properties of the GFP-based filter will lead to better characterisation of the protein-polymer matrix and rational design of improved components.
Objective
In the field of lighting, a new technology has recently appeared: the bio-LED, which makes use of derivatives of the green Fluorescent Protein (FP) as downcoverting materials. This provides a cheap, green and easy to procure replacement for the currently used rare-earths-based downconverting filters, whose sustainability is hindered by the associated costs and their ecological impact. Despite the encouraging results obtained so far, the bio-LED needs improvements in terms of stability and performances in order to become competitive in the market. BIOS (BIO-led through Simulations) aims at addressing these issues by studying the fundamental structural and electronic properties of the FP-based filter at realistic, working conditions (i.e. high temperature) using a theoretical and computational approach. This will allow us to characterise the interactions that stabilise the FP-polymer matrix mixture, thus providing guidelines for the chemical design of components of the downconverting filters to improve thermal stability. Hybrid approaches that makes use of molecular dynamics, molecular mechanics, quantum mechanics and analytical models will be employed to first characterise the interactions that stabilise FPs in non-physiological conditions while allowing them to maintain their optical activity, and then to study in detail the deactivation paths of the FPs, with a particular focus on thermal dissipation procceses, which currently constitute the main obstacle to the market competitiveness of the bio-LED technology. Through BIOS we will therefore obtain insight in the strategies to adopt to improve the performances of the final device.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences chemical sciences polymer sciences
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2021-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
28006 Madrid
Spain
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