Objective
Plant diseases lower crop yields significantly, and thereby threaten food-security worldwide. Powdery mildew fungi is a severe pathogen on numerous food-crops. Generating food-crops resistant to these fungi would be a major step forward in the continuous fight between plants and pathogens, and it would tip the balance in the favor of food-security. The proposed project will majorly contribute to this goal by elucidating the immunity related processes occurring upon fungal infection and will allow to develop breeding strategies to heighten plant immunity. The barley powdery mildew fungus (Blumeria hordei) causes disease by secreting hundreds of effector proteins into the barley tissue. One of the hallmarks of immunity is the formation of a structure called papilla, at the site of fungal penetration, which limit the damage to the plant. Evolutionary adapted fungi can easily overcome this. However, the pathway for secretion of proteins and other components to the papilla is not well understood. There is thus a need to increase our understanding of how this secretion process occurs during immunity. My host lab has uncovered that the membrane trafficking leading to papilla formation occurs by novel mechanisms not previously studied in plants. In the proposed project, I will explore this highly complex field by identifying a list of fungal effectors which target this pathway, and I will use these effectors to find specific components of it. Ceramides are predicted to play a role in the secretion of extracellular vesicles during this papilla formation in mammals, therefore, I will additionally take a targeted approach to characterize their role in plants. My strong background and solid track-record, the expertise and experience of the host supervisor, together with the infrastructure and encouraging scientific atmosphere at the host department will synergistically maximise the output of the proposed project, and develop and diversify my skills as an independent researcher.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology mycology
- agricultural sciences agriculture, forestry, and fisheries agriculture grains and oilseeds cereals
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1165 KOBENHAVN
Denmark
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.