Objective
Recent studies have shown that plants locally increase zinc concentrations to fend-off invading microbes, a process in which Zn2+- ATPases HMA2 and HMA4 are essential. ZINMUNITY aims to unveil the molecular mechanisms controlling plant-zinc based immunity, connect it to the known defence signalling pathways, and determine the mechanisms allowing HMA2 and HMA4 to locally increase zinc levels. To do this, I will be trained in the patho-system Arabidopsis thaliana-Plectosphaerella cucumerina BMM, in metal imaging, confocal microscopy, transcriptomic and proteomic data analyses, and biochemistry of Zn2+-ATPases. In exchange, I will contribute with my experience in protein-protein interaction and in computational analyses of protein docking. At the end of this project, I should not only have placed zinc-toxicity mechanisms within the general plant immune responses, but also identified the molecular patterns triggering it, and determined the identity of the zinc-donor proteins to HMA2 and HMA4, impacting both the plant immunity and nutrition areas. As relevant will be setting the foundations for the development of new strategies of crop protection based on the use of zinc enriched bio-estimulants or fertilizers, with important societal (reduction of polluting/toxic and expensive pesticides), and economical implications (lower costs for farmers, new markets for the zinc-fertilizer industry). Moreover, this proposal will set the basis for me to reach a position of scientific independence, since ZINMUNITY will deliver a number of interesting genes for future characterization. This next career step will also be facilitated by many of the transferable skills acquired, such as grant applications, paper publication, research supervision and FAIR data management.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences inorganic chemistry transition metals
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences physical sciences optics microscopy
- medical and health sciences health sciences nutrition
- agricultural sciences agriculture, forestry, and fisheries agriculture
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
28040 Madrid
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.