Objective
Chirality is an essential property of nature, producing and regulating fundamental phenomena in living matter. Chiral compounds are widely used in medicine, clinical, pathological, and other fields. Different enantiomers of chiral molecules have significant differences in pharmacological activities, metabolic effects, toxicity, and even opposite effects. Since most chiral compounds exist in the racemic form, it is important to develop strategies for rapid and efficient separation and purification of chiral compounds to deal with inevitable future threats such as diseases and viruses. Although many techniques for chiral resolutions have been developed over the years, most of them are impeded by low efficiency and accuracy, high energy consumption, tedious preparation and operation and high cost. Therefore, I propose a project, CRMS “Chiral Resolution using Microfluidics and helical Supramolecular polymers” which aims to develop a simple diffusion-based strategy for chiral resolution by incorporating helical supramolecular polymers (HSPs). In this project, I will combine the ability of HSPs to recognize the handedness of chiral molecules through non-covalent interactions with the diffusion-based separation ability of microfluidics for the enantio-separation of chiral molecules. I chose microfluidics for chiral resolution because it is a cost-effective and energy-efficient technique that takes advantage of the natural flow properties of the fluids entering the flow reactor for diffusion-based separation. CRMS project will not only start a new area of research in the junction of supramolecular chirality and flow chemistry but also have applications in pharmaceutical and cosmetic industries for enantio-separation of chiral drugs/ingredients.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences classical mechanics fluid mechanics microfluidics
- natural sciences biological sciences microbiology virology
- natural sciences chemical sciences polymer sciences
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
28049 Madrid
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.