Project description
Gauging the benefits of timed exercise regimen for prediabetic adults
Regular exercise is an effective and easy way for prediabetics to lower blood glucose levels. However, time constraints often prevent individuals from keeping to a fitness regimen. Alternatively, time-saving workouts such as high-intensity interval training (HIIT) and timed exercise provide health benefits, but their effectiveness in restoring metabolic health in prediabetic adults is uncertain. Supported by the Marie Skłodowska-Curie Actions programme, the REALIGN project will monitor prediabetic adults participating in a 12-week HIIT programme to determine whether the workout is more beneficial at a specific time of day to improve glucose excursion profile and fuel switching. As a follow-up, it will interview participants to assess their views and experiences on the timed HIIT programme.
Objective
Being more active is an important part of treatment for adults with prediabetes. Exercise is one of the simplest and most effective ways to bring down blood glucose levels. However, lack of time is a common barrier to performing exercise regularly. The high-intensity interval training (HIIT) and timed exercise are two new exercise approaches which require lesser time commitment, but their health benefits are equally similar to the traditional exercise modality. But whether combining both principles (HIIT and timed exercise) could restore metabolic health in adults with prediabetes remains unknown. Using a mixed-methods approach, the REALIGN project aims to investigate whether performing HIIT at a certain time of day is more beneficial than performing it at another time of day to improve glucose excursion profile and fuel switching. Whereas the secondary aim is to explore the views and experiences of adults with prediabetes on timed HIIT program. To achieve these aims, adults with prediabetes will be randomly assigned to a 12-week HIIT program either in the morning or afternoon. A continuous glucose sensor will be used to assess the changes in their blood glucose fluctuation profile. Whereas two types of calorimeters (respiration chamber and ventilated hood system) will be used to assess the body’s ability to switch between carbohydrates and fats as energy sources in response to feeding and fasting conditions. At the end of the program, some of the participants will be interviewed to explore their perceptions of the timed HIIT exercise. This interdisciplinary project will take place at the German Diabetes Center (DDZ) which houses cutting-edge infrastructures in exercise and metabolism research. This project is linked to key training aiming to advance the fellow’s competency in experimental and transferable skills to enhance professional maturity and develop independence.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine endocrinology diabetes
- natural sciences biological sciences biochemistry biomolecules carbohydrates
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
- engineering and technology environmental engineering energy and fuels
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Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2023-PF-01
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40225 Duesseldorf
Germany
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