Project description
More efficient, biocompatible devices that better mimic how neurons function
Neurological diseases are a major global health challenge as they affect one in three people worldwide. With the support of the Marie Skłodowska-Curie Actions programme, the OASYS project aims to address this by developing advanced organic materials and devices that mimic how neurons work. These devices, called conductance-based organic electrochemical neurons, emulate neuron-like signals but are limited in their ability to generate biologically plausible spike frequencies. They also require high power consumption, which hinders their integration with biological systems. OASYS plans to tackle these issues by creating new materials that operate faster, use less power and produce more realistic neuron-like signals. Combining innovative material design, material characterisation and device engineering, OASYS will create wearable devices that can integrate seamlessly with biological systems.
Objective
Neurological diseases are now the leading contributor to the global health burden, affecting one in three individuals worldwide. In response to this critical issue, the development of innovative organic mixed ionic-electronic conductors (OMIECs) that emulate the ion-regulated electronic conductivity and dynamics of biological ion channels when implemented in organic electrochemical transistors (OECTs) has paved the way for electronic devices capable of replicating neuronal functionality, namely conductance-based organic electrochemical neurons (c-OECNs). Despite the progress towards emulating biological neuron functions, current c-OECNs are limited by their inability to generate biologically plausible spike frequencies and their high power consumption, which hinder their integration with biological systems. In this sense, OASYS plans to overcome this challenge by developing innovative OMIECs with optimized ambipolarity characteristics and fabricating wearable and biorealistic c-OECNs that can be fully integrated with biological systems. This will be realized by using rationally designed bithiophene imide (BTI)-based polymers that operate at low gate voltages, enabling faster OECT devices with reduced power consumption and enhanced spike frequencies. OASYS integrates cutting-edge polymer design, advanced material characterization, and innovative device engineering in an application-oriented approach to tackle critical challenges such as antiambipolar tunability, selective sensing, wearability, and biointegration.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
581 83 Linkoping
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.