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Unraveling the impact of polyfluoroalkyl substances on aquatic microbial communities to create biodegrading microbial consortia between mixotrophs and fungi

Project description

Developing microbial consortia to biodegrade polyfluoroalkyl substances

Polyfluoroalkyl substances (PFASs), widely used in household products, are often transported in wastewater and end up in other aquatic ecosystems. They have been found in over 90 % of European rivers and are known endocrine disruptors. Supported by the Marie Skłodowska-Curie Actions programme, the MIXFUN project will investigate how PFASs affect aquatic microbial communities, aiming to identify organisms that can biodegrade PFASs. Based on the findings, it will develop biological systems (microbial consortia) of organisms with high biodegradation potential and establish optimal conditions (ultraviolet radiation and temperature) for their growth and biodegradation capacity. Ultimately, MIXFUN expects that these consortia could provide a natural and sustainable way to biodegrade PFASs for the benefit of both human health and ecosystems.

Objective

Polyfluoroalkyl substances (PFAS) are compounds widely used in commercial and industrial applications. Due to their presence in many household products, they are often found in wastewater effluent and urban runoff, from where they reach other aquatic ecosystems. PFAS present several significant issues associated to their persistence, transport (they have been detected in more than 90% of European rivers); and health effects as endocrine disruptors. The main objective of the MIXFUN project is to understand how PFAS may impact the structure of aquatic microbial communities by favoring organisms capable of degrading them, and to use this information to develop biological systems (microbial consortia) based on organisms with high biodegradation potential in combination with physical conditions (ultraviolet radiation-UVR and temperature) that enhance their capacity. We know that the presence of organic carbon in PFAS molecules could be their Achilles' heel, and that those microbial organisms capable of using this carbon could biodegrade the compounds in a cheaper and more sustainable manner than physico-chemical treatments. Additionally, temperature can influence biodegradation metabolism, while UVR has shown a photodegradative effect on PFAS. Since microorganisms coexist in their natural environment with fluctuations in UVR and temperature, our proposal to create a hybrid system of microbial consortia under various UVR and temperature conditions could yield satisfactory results. To achieve this, we plan to identify mixotrophs and fungi that are favored through a gradient of PFAS-contaminated lakes and subsequently develop mixotroph-fungi consortia. By combining empirical data and predictive models, we will be able to determine the optimal growth and biodegradation conditions for these consortia. As a result, we expect to determine how the use of these consortia can take the degradation of PFAS to the next level, benefiting both human health and ecosystems.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

(opens in new window) HORIZON-MSCA-2024-PF-01

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Coordinator

UNIVERSIDAD DE GRANADA
Net EU contribution
€ 194 074,56
Address
CUESTA DEL HOSPICIO SN
18071 Granada
Spain
Region
Sur Andalucía Granada
Activity type
Higher or Secondary Education Establishments
Links
Total cost
No data