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A Digital Twin Enabled Multiplexed Sensors for Chronic Wound Management (TWINSENSE)

Project description

Digital twin-enabled smart bandages for chronic wounds

Chronic wounds such as diabetic ulcers and pressure sores often resist healing, leading to pain, infections, and even amputations. The TWINSENSE project, supported by the Marie Skłodowska-Curie Actions programme, aims to transform chronic wound care by developing a digital twin platform. This system uses wearable smart bandages embedded with printed multiplex sensors to continuously monitor key wound biomarkers such as pH, temperature and urea. Sensor data will feed into a digital twin framework, enabling the creation of a high-fidelity virtual replica of the wound. An AI-driven scenario-maker module will generate predictive models of healing based on sensor readings and provide real-time therapeutic insights. The goal is personalised, timely care that accelerates healing, reduces complications and lowers healthcare costs.

Objective

TWINSENSE is a project aimed at digitizing wound management through the development of a digital twin (DT) of chronic wounds through a multiplexed sensor system. The project integrates data from a custom-designed, wearable multimodal sensor with machine learning (ML) algorithms to develop the DT, enabling real-time analysis of wound biomarkers and accurate prediction of healing outcomes. This will facilitate timely therapeutic interventions, reducing the risk of complications such as amputations in chronic wounds. TWINSENSE focuses on developing screen-printable formulations of metal-decorated reduced graphene oxide (rGO) derivatives to create multimodal sensors on wearable bandages. These sensors, in combination with a wearable electronic circuit, will continuously monitor wound parameters (pH, temperature, urea) to generate comprehensive ML training datasets. The datasets will be employed to develop the DT using knowledge graph-based data modelling techniques. The DT will also feature a Scenario-Maker module, capable of processing data from the multimodal sensors to simulate various healing scenarios, predicting potential complications, and recommending optimized treatment strategies in real time. By addressing the unmet need for advanced chronic wound care, which affects over 60 million people globally, TWINSENSE aims to improve patient outcomes and reduce healthcare costs. Additionally, TWINSENSE has the potential to foster an entrepreneurial ecosystem around digital wound care technologies, driving revenue generation and contributing to the sustainable development of healthcare systems.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

(opens in new window) HORIZON-MSCA-2024-PF-01

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Coordinator

EDINBURGH NAPIER UNIVERSITY
Net EU contribution
€ 276 187,92
Address
COLINTON ROAD 219
EH14 1DJ Edinburgh
United Kingdom
Region
Scotland Eastern Scotland Edinburgh
Activity type
Higher or Secondary Education Establishments
Links
Total cost
No data

Partners (1)