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Accounting for human behaviour in risk assessments of zoonotic spillover and international spread of infectious diseases in scenarios of global change

Project description

Mapping future pandemic risks under global changes scenarios

Zoonotic spillovers and the global spread of infectious diseases pose a significant threat. Their risk depends on human-animal population interactions and mobility patterns, influenced by socio-economic and environmental factors. Changes in these behavioural factors will affect the likelihood of future disease transmission. With the support of the Marie Skłodowska-Curie Actions programme, the KASSANDRA project will create maps of future spillover and global spread risks for infectious diseases of bat-origin. It will analyse scenarios related to climate change, land-use changes, and demographic and economic development. The risk maps will represent key evidence-based knowledge for preparing our society to future global health threats.

Objective

Zoonotic spillover and the subsequent global spread of infectious diseases represent an increasing global threat to our society. Projections of future zoonotic spillover events are based on the spatial copresence of human and animal host population and risk assessments of local outbreaks to spread globally rely on observed mobility data. However, human behaviour is a complex phenomenon driven by socio-economic, environmental and demographic factors that altogether shape human mobility patterns and the human-host contact rate, which is key to zoonotic spillover. By impacting these drivers, future global economic, demographic, environmental and climate change will alter the risk of zoonotic spillover and global spread of infectious diseases.
Here, focusing on scenarios of future climate and land-use change, demographic and economic development (SSP-RCP), I intend to (i) produce maps of future spillover risk that account for the behavioural determinants shaping human-host contact and (ii) assess the risk of the global spread of future infectious diseases. I will focus on infectious diseases of bat origin and I will estimate the effect of economic, demographic, environmental and ecological drivers in defining human-bat contact rates. Drawing on these results I will produce synthetic human-bat contact data and maps of future risk of zoonotic spillover. Then, I will use the risk maps to assess the risk of the global spread of future infectious diseases. To this end, I will use a global metapopulation model informed by projections of international human mobility patterns that will be obtained from a global international human mobility model that I will develop. In doing so I will include key drivers and behavioural processes (e.g. economic constraints) of human mobility. The outcome of the project will advance our understanding and preparedness to future zoonotic spillover and pandemic risks by accounting for human behaviour drivers in a context of global changes.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-TMA-MSCA-PF-GF - HORIZON TMA MSCA Postdoctoral Fellowships - Global Fellowships

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Call for proposal

(opens in new window) HORIZON-MSCA-2024-PF-01

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Coordinator

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Net EU contribution
€ 413 379,72
Address
RUE DE TOLBIAC 101
75654 Paris
France
Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
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Total cost
No data

Partners (1)