Project description
Graphene biosensors for accurate infectious disease diagnostics
Early diagnosis of bacterial infections ideally requires tools that feature high speed, high throughput, accuracy and affordability, while being easy to use. With the support of the Marie Skłodowska-Curie Actions programme, the BUG-ID project will establish an interdisciplinary doctoral programme to develop technology for such a tool based on the 2D nanomaterial graphene. Academia, the healthcare sector and private enterprises will train doctoral candidates in research ranging from nanotechnology, AI-based data analysis and materials science to molecular microbiology, biochemistry and infectious disease medicine. Working together, they will identify appropriate biomarkers and structurally engineer receptors, functionalise graphene sensors for integration with the receptors, as well as miniaturise sensors and optimise signal readouts using machine learning and explainable AI.
Objective
The World Health Organization has emphasized the importance of early and accurate diagnosis of bacterial infections. An ideal diagnostic tool would possess high speed, high throughput, accuracy, low cost and simplicity of use for the clinical laboratory or bed-side applications. Diagnostic tools that possess all these properties currently do not exist. To address this knowledge gap, in the BUG-ID consortium, seven European universities, one research institute, one hospital and six private companies have teamed up. Our consortium will train 15 doctoral candidates with skills in interdisciplinary research, spanning from nanotechnology and materials science to molecular microbiology, biochemistry, infection medicine to AI-based data analysis. Private sector participants will bring their full capacity to bear on intersectoral training, allowing doctoral students to forge links between science and innovation. At the core of the BUG-ID concept is the 2D nanomaterial graphene. Versatile surface chemistry, sensing capacity and possibility of integration with electronic and optical devices will be the key properties of graphene exploited by our consortium. Scientific challenges we will tackle will include the identification of suitable biomarkers for infection in complex environments (background of bacterial commensals), structural engineering of appropriate receptors for identified biomarkers, functionalization of graphene sensors with the receptors and their integration into functional sensors, miniaturization of sensor technology and optimization of complex signal readouts using machine learning techniques and explainable AI. To pave the way for building such game-changing technology, BUG-ID doctoral students will have to work together as a team, drawing competence from distant scientific disciplines, and moving across sectoral boundaries. In doing so, they will receive training that empowers them to become future leaders in science and innovation.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors biosensors
- engineering and technology nanotechnology nano-materials two-dimensional nanostructures graphene
- natural sciences biological sciences microbiology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-DN-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
2800 Kongens Lyngby
Denmark
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.