Project description
Lipid biology for diagnostics and therapy
Lipids play a key role in diseases like cancer, cardiovascular disease, kidney disease, and chronic inflammation. Studying lipids could lead to new treatments. As such, researchers are taking a closer look at lipid metabolism in diseases with the aim of developing tools for detecting and imaging lipids. Supported by the Marie Skłodowska-Curie Actions programme, the LipiBRIGHT project aims to train young researchers in lipid biology, new technologies, and clinical applications. Forming a group of leading institutes, small and medium-sized enterprises, and industry partners, doctoral students will investigate lipid biomarkers, disease mechanisms, and clinical uses. The project’s overarching goal is to speed up the application of lipid research into new diagnostics and therapies.
Objective
Recent insights revealed new, decisive roles for lipids in cardiovascular disease, chronic kidney disease, cancer and chronic inflammation. Lipid targeting may offer novel treatment opportunities for these four high-impact diseases, complementary to the currently available, insufficiently effective therapies. However, developing effective diagnostic, preventive and therapeutic solutions requires deeper insights into lipid metabolism in disease as well as improved methods of lipid detection and imaging. Furthermore, an increasing interest in lipids in clinical applications, demonstrated by our associated partners, generates job profiles requiring novel, lipid-focused, interdisciplinary training. LipidBRIGHT is the first lipid-focused ITN designed to address the unmet medical need to i) better understand lipid metabolism in disease and ii) train young scientists in the emerging lipids field, associated technologies and clinical applications, this to speed-up understanding of lipid-associated diseases and translation into novel strategies for disease diagnosis, prevention and treatment.
LipidBRIGHT comprises 6 forefront-running, interdisciplinary and intersectoral research institutes and 2 SMEs with complementary expertise in lipid-associated diseases, technology and translation, supported by 4 academic and 1 international research institute, 3 SMEs, 4 international companies, 2 stakeholder-representing organisations and 1 international organisation of mixed academic/private members. With established cooperations, we will train doctoral students around three pillars: (i) Lipid biomarkers, artificial intelligence and disease modelling, (ii) Lipid-associated pathology & disease mechanisms, and (iii) Lipid application in clinics & industry. This will provide excellent scientific, technological and transferable skills to generate innovative insights in the opportunities of lipid research, and boost EU competitiveness in lipid research, translation and application.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules lipids
- medical and health sciences clinical medicine cardiology cardiovascular diseases
- medical and health sciences clinical medicine oncology
- medical and health sciences basic medicine pathology
- medical and health sciences clinical medicine nephrology kidney diseases
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-DN-01
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6200 MD Maastricht
Netherlands
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Participants (8)
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3000 Leuven
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3500 Hasselt
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07747 Jena
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Participation ended
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54052 Nancy Cedex
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3584 CS Utrecht
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541 35 SKOVDE
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34000 Montpellier
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75654 Paris
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Partners (17)
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3012 Bern
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74909 Baden-Baden
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1000 Bruxelles / Brussel
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54500 Vandoeuvre-les-Nancy
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3600 Genk
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4410 Liestal
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55218 Ingelheim
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52074 Aachen
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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52074 Aachen
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171 77 STOCKHOLM
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54 128 Skovde
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2719 EK Zoetermeer
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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61352 Bad Homburg
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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3584 CT Utrecht
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
67663 Kaiserslautern
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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34090 Montpellier
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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54052 Nancy Cedex
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