Project description
Brain Health in Menopausal Women
Menopause is a critical stage in women’s lives, with significant implications for health. This transition affects brain health and increases the risk of diseases like Alzheimer’s. Yet menopause-related changes remain poorly understood and lack effective interventions. With the support of the Marie Skłodowska-Curie Actions programme, the MenoBrain project will train 15 doctoral candidates to address challenges related to menopause and brain health. Participants will work within a multidisciplinary international network of 18 organisations. Using advanced methods like MRI, DTI, PET, EEG, and host-microbiome modelling, the project will explore how hormonal changes during menopause and therapies impact cognitive health, gut-brain communication, and ageing. It will identify biomarkers for early cognitive dysfunction detection, improve therapies, and promote personalised healthcare for menopausal women.
Objective
With the global population of menopausal women projected to reach 1.2 billion by 2030, menopause represents a critical yet understudied period in women's health. Hormonal changes during this transition pose significant risks to brain health, cognitive function, and emotional well-being, while increasing vulnerability to age-related diseases such as Alzheimer's disease. Despite its profound societal relevance, menopause-related brain changes remain poorly understood, with limited biomarkers and evidence-based interventions available.
MenoBrain aims to fill this gap by training a new generation of 15 doctoral candidates to address the pressing challenges of menopause-related brain health. The DCs will work within a multidisciplinary and international network of 18 participants (11 beneficiaries and 7 partners) spanning neuroimaging, neuropsychology, endocrinology, microbiome research and bioinformatics. MenoBrain will employ cutting-edge methods including advanced neuroimaging (MRI, DTI, PET, EEG), host-microbiome modelling, and computational BrainAGE models. This integrated approach will explore how hormonal changes associated with menopause and interventions such as menopausal hormone therapy impact cognitive health, gut-brain communication, and aging trajectories.
The programme combines scientific excellence with a robust training structure to equip MenoBrain doctoral candidates with expertise in interdisciplinary and intersectoral research, advanced technologies, and transferable skills. By leveraging state-of-the-art infrastructure, MenoBrain will discover biomarkers for early detection of cognitive dysfunction, improve therapeutic strategies, and advance personalized healthcare for menopausal women.
MenoBrain not only addresses a critical gap in women's health research, but also aligns with the EU's agenda to promote healthy aging, gender-specific healthcare, and fostering innovative training for the next generation of leaders in science and industry.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology cognitive neuroscience
- medical and health sciences basic medicine neurology neurodegenerative diseases dementia alzheimer
- medical and health sciences clinical medicine endocrinology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks
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Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-DN-01
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07747 Jena
Germany
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Participants (10)
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0319 Oslo
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72074 Tuebingen
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2311 EZ Leiden
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751 05 Uppsala
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23562 Lübeck
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75654 Paris
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01513 Vilnius
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08005 Barcelona
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5020 Salzburg
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00790 Helsinki
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Partners (9)
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1736 SENNINGERBERG
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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10969 Berlin
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3735 MT Bosch En Duin
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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58638 Iserlohn
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3137 GV Vlaardingen
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82515 Wolfratshausen
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08002 Barcelona
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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24118 Kiel
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54052 Nancy Cedex
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