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MultiScale phenomena in Radiation Damage

Project description

Studying radiation damage across scales

Understanding how radiation affects biological systems is crucial for advancements in particle therapy and radiobiology, which are used to target and destroy cancer cells. With the support of the Marie Skłodowska-Curie Actions programme, the MS-RADAM project will pioneer a new approach to reveal key nano- and larger-scale radiation damage. Using multiscale modelling and different experimental techniques, researchers seek to examine radiation effects across different time and size scales – from charged particle movement in biological media to slower chemical and thermal processes after irradiation. Detailed understanding of these processes will help improve applications in cancer treatment and other radiation-based technologies. MS-RADAM will also train 14 doctoral candidates, equipping them with the methodology and skills to drive future innovations in radiation research and technology.

Objective

The MS-RADAM DN will deliver a state-of-the-art research programme that will pioneer a new approach to reveal key nano- and larger-scale radiation biodamage phenomena based on multiscale modelling (MM) and its thorough validation using advanced experimental techniques and technological applications. In particular, the MS-RADAM research programme will focus on obtaining an advanced understanding of Radiation Damage (RADAM) phenomena induced by ion irradiation in biomolecular and biological systems relevant to the application of this knowledge in particle therapy and many other relevant areas of research and technology.

The unique feature of the MS-RADAM research programme is the MM description and measurement of key processes and phenomena occurring on different temporal and spatial scales during ion-beam irradiation incorporating: (i) propagation of charged particles in biological media, (ii) radiation-induced fast quantum processes within biomolecular environments, (iii) characterisation of the time and spatial evolution of track structures and localised energy deposition, (iv) slower nanoscale post-irradiation relaxation, chemical and thermalisation processes occurring in the irradiated biological media, (v) evaluation of biodamage accounting for specific radiobiological effects.

To initiate such a programme and to provide industry, radiotherapy research community and many other related communities with a cohort of skilled researchers, MS-RADAM DN will train 14 Doctoral Candidates (DCs) in the methodology and skills needed for this emerging area of research and technology.

MS-RADAM DN contains leading academic and industrial partners with the necessary experience to provide the international, interdisciplinary and intersectoral training needed for the MS-RADAM research programme, whist also providing the DCs a unique opportunity to gain comprehensive training in the complementary and entrepreneurial skills for their further career development.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks

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Call for proposal

(opens in new window) HORIZON-MSCA-2024-DN-01

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Coordinator

MBN RESEARCH CENTER GGMBH
Net EU contribution
€ 580 544,64
Address
AM STEINCHEN 3C
61479 GLASHUETTEN
Germany
SME
Yes
Region
Berlin Berlin Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost
No data

Participants (9)

Partners (12)