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Additive Manufacturing of Crack-Free, Ductile Zirconia-Based Composite for Medical Implants

Project description

Transforming dental restoration with ductile ceramics

Restoring oral health is vital to quality of life, yet current metal-free implants often suffer from material brittleness and manufacturing defects. Supported by the Marie Skłodowska-Curie Actions programme, the AMICERA project aims to address these challenges by developing personalised dental implants from innovative ductile ceramic composites. By utilising advanced stereolithography-based additive manufacturing and AI-powered X-ray scanning, the project will ensure each implant is perfectly tailored to a patient’s unique anatomy while remaining structurally reliable. Beyond customisation, the project will provide fundamental insights into manufacturing processes to eliminate flaws and enhance durability. This breakthrough will expand treatment options for Europe’s ageing population and for those requiring metal-free solutions, ultimately transforming modern implantology, enhancing patient quality of life and broadening access to care.

Objective

Reconstruction of craniomaxillofacial and oral hard tissues is crucial for restoring function and quality of life (QoL) in patients with extensive bone defects or edentulism. However, the growing demand for personalised, metal-free implants is hindered by several critical limitations, including the inherent brittleness of ceramic materials, limited customisation, and low manufacturing reliability due to processing-related defects.
AMICERA addresses these challenges by developing reliable, patient-specific dental implants from novel ductile ceramic composites (Ce-TZP–Al2O₃–SrAl₁2O₁₉) using stereolithography-based additive manufacturing (AM), combined with a non-destructive defect detection strategy via X-ray computed tomography (XCT) enhanced by artificial intelligence (AI). The project will generate fundamental insights into the AM processing–structure–property relationships of this ductile ceramic material, enable its transformation into complex implants tailored to individual anatomies and ensure implants' reliability through AI-powered defect analysis.
By pioneering a transformative, metal-free approach for personalised reconstructive therapies, AMICERA will address urgent public health needs linked to Europe’s ageing population. Ultimately, this project will expand treatment options for patients currently excluded from conventional implant therapy or who are unable or unwilling to receive metal-based solutions, thus enhancing QoL, broadening access to care, and potentially transforming modern implantology.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

(opens in new window) HORIZON-MSCA-2025-PF

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Coordinator

INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON
Net EU contribution
€ 226 420,56
Address
20 AVENUE ALBERT EINSTEIN
69621 VILLEURBANNE CEDEX
France
Region
Ile-de-France Ile-de-France Paris
Activity type
Higher or Secondary Education Establishments
Links
Total cost
No data