Skip to main content
Go to the home page of the European Commission (opens in new window)
English en
CORDIS - EU research results
CORDIS

Degradable on-demand conjugated polymer systems for transient bioelectronics

Project description

Degradable organic electrochemical transistors for sustainable bioelectronics

Bioelectronic devices, whether in the body or the environment, should safely degrade after use, but most materials currently persist indefinitely. Organic electrochemical transistors (OECTs) are among the most promising bioelectronic platforms. Achieving controlled degradation – particularly in the n-type variants essential for detecting biologically relevant anions – is problematic. Conjugated polymers are the most important part of OECTs, but ensuring simultaneous operational stability and degradability is challenging. With the support of the Marie Skłodowska-Curie Actions programme, the DOPTE project aims to solve this with a new class of degradable n-type conjugated polymers. The resulting design guidelines could reduce the need for surgical device retrieval and advance sustainable next-generation bioelectronics.

Objective

The rapid growth of bioelectronics creates an urgent need for sustainable and degradable materials that can safely disappear after use, avoiding long-term persistence in the body or the environment. Organic electrochemical transistors (OECTs), with low-voltage operation, high ionic sensitivity, and good biocompatibility, are among the most powerful device platforms in bioelectronics. While degradation has been shown in selected p-type OECTs, progress on n-type counterparts is very limited. This gap is critical, as n-type OECTs are indispensable for detecting biologically relevant anions and enabling complementary circuits. To date, no reliable strategies exist to achieve controlled degradation of bioelectronics under physiologically relevant conditions—an essential requirement for biomedical and environmental applications.

Conjugated polymers are the most important part of OECTs, combining electronic functionality with tunable chemical structures. Yet designing systems that deliver both high charge transport and predictable degradation remains highly challenging, since the structural features stabilizing electronic states often resist breakdown, whereas degradable motifs tend to compromise stability and conductivity.

The DOPTE project addresses this challenge by creating degradable n-type conjugated polymers that unite electronic performance with controlled degradation. The central strategy is to integrate cleavable motifs into high-performance conjugated backbones, enabling degradation under physiological conditions or through near-infrared activation. The project will establish design guidelines for degradable bioelectronics, with the potential to reduce surgical retrieval in biomedical devices and support sustainable materials for next-generation bioelectronics. It will provide me with key interdisciplinary training to strengthen my development as an independent researcher.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

See all projects funded under this funding scheme

Call for proposal

(opens in new window) HORIZON-MSCA-2025-PF

See all projects funded under this call

Coordinator

STOCKHOLMS UNIVERSITET
Net EU contribution
€ 236 340,00
Address
UNIVERSITETSVAGEN 10
10691 Stockholm
Sweden
Region
Östra Sverige Stockholm Stockholms län
Activity type
Higher or Secondary Education Establishments
Links
Total cost
No data