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A Multi-Modal Spectroelectrochemical Sensor Platform for the Real-Time Detection of Per- and Polyfluoroalkyl Substances (PFAS) using Advanced Data Fusion

Project description

Real-time multi-modal detection of PFAS

Per- and polyfluoroalkyl substances (PFAS) consist of thousands of synthetic chemicals that exist everywhere. Exposure to PFAS can occur from various sources such as food and food packaging materials, cosmetics, products available to consumers, ambient air, indoor air and dust and drinking water. While these contaminants may cause adverse effects on human health and the environment, their detection is expensive, time-consuming and difficult to achieve in real time. Supported by the Marie Skłodowska-Curie Actions programme, the SENS-PFAS project will develop a portable real-time monitoring system that can improve detection and minimise the risk of false positives. It will combine both electrochemical and optical detection with the use of redox-active probes.

Objective

"Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants associated with serious health risks, including chronic diseases and cancer. Widely used in various industries, they are known as ""forever chemicals"" due to their stability. While traditional detection methods like LC-MS/MS are accurate, they are costly and time-consuming, making them impractical for on-site, real-time monitoring. With regulatory actions, such as the European REACH proposal seeking to restrict PFAS use, there is a critical need for faster, portable detection technologies.

This project addresses this challenge through the development of an integrated, real-time monitoring system based on multi-modal spectroelectrochemistry. My innovative approach combines electrochemical and optical (fluorescence/absorbance) detection by using a specialized redox-active probe. This strategy enhances detection sensitivity and robustness by requiring a correlated, two-dimensional signature for a valid detection, significantly reducing the risk of false positives that limit current single-signal sensors. Core objectives include the systematic characterization of these multi-modal probe-PFAS interactions, the development of advanced multivariate models to deconvolve the complex datasets, and the design of a portable platform that integrates these methods.

This project will be the first to systematically develop and validate a multi-modal spectroelectrochemical sensor for priority PFAS compounds. By delivering an accessible, high-confidence, real-time detection tool, we aim to improve environmental monitoring, helping regulators and industries better manage PFAS contamination and protect public health."

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

(opens in new window) HORIZON-MSCA-2025-PF

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Coordinator

NORGES MILJO-OG BIOVITENSKAPELIGE UNIVERSITET
Net EU contribution
€ 251 578,56
Total cost
No data