Objective
Affecting nearly 15 % of children and adolescents worldwide, neurodevelopmental conditions (NDDs) in children are a growing public health concern in Europe and worldwide. NDDs may be exacerbated by poor dietary habits, via altering the composition and function of the gut microbiota. Communication between the gut microbiome and the brain, via the gut-brain axis, has emerged as a potential target to support brain health. However, the molecular mechanisms underpinning these relationships are poorly understood, particularly the specific dietary patterns, microbes, and microbial metabolites involved in modulating gut-brain communication. This fellowship aims to investigate the molecular mechanisms through which early-life diet influences gut microbiome-brain communication, and the impact this has on neurocognitive outcomes. First, the fellow will perform advanced statistical analysis on the already available existing data of the MAMI cohort to explore the interplay between diet, microbiome, and neurocognitive outcomes in children. Next, microbial signatures associated with neurocognitive outcomes will be investigated at the molecular level through faecal microbiota transplantation (FMT) in mice. Finally, to deepen mechanistic insights into host-microbe-brain interactions, the effects of microorganisms and microbiome-derived metabolites identified in human and animal studies on gut and blood-brain barrier function will be studied in vitro models. The fellow will receive advanced training in data analysis at the host institution and in cell-based methodologies at both the host and secondment institutions. By bringing in vivo methods to the host lab, the fellow will boost its ability to translate and validate findings from human studies. This fellowship will support the fellow’s transition to an independent, interdisciplinary scientist, equipped to lead impactful research on the diet-microbiota-brain axis.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences data science
- medical and health sciences health sciences public health
- medical and health sciences health sciences nutrition
- medical and health sciences clinical medicine transplantation
- natural sciences biological sciences microbiology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2025-PF
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
28006 Madrid
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.