Objective
This project is aimed at the molecular characterization of
structure-function relationships involved in viroid-host cell interaction. The experimental system will be peach latent mosaic viroid (PLMVd) infecting peach seedlings. PLMVd is a non-typical viroid since contrary to most other members of the family, contains hammerhead ribozymes that are involved in vitro, and very probably in vivo, in the self-cleavage of their strands of both polarities. The existence of several natural isolates of PLMVd of different pathogenicity together with the relatively short time required for the induction of symptoms, makes this system very attractive. Full-length cDNA clones of PLMVd, constructed by reverse transcription-PCR amplification, will be used to infect peach seedlings in order to map regions involved in replication and/or pathogenesis. Site-directed mutagenesis will allow to determine the importance of specific residues within these regions as well as to confirm and characterize elements of tertiary structure in PLMVd.
Fields of science (EuroSciVoc)
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
46022 VALENCIA
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.