Objective
The homeobox gene goosecoid is present in all vertebrate species. In the mouse it is first transiently expressed during gastrulation in the primitive streak and from E10.5 to E14.5 in the branchial arches, frontonasal mass and limb buds. In Xenopus embryos goosecoid mRNA injection has demonstrated a role in the Organizer phenomenon. However, homozygotic goosecoid mutant mice have a phenotype which is only related to its late phase of expression.
Southern blotting analysis has indicated the existence of additional goosecoid-related genes which might compensate for the absence of a phenotype at the gastrula stage. My research project will be focused on the identification of these additional mouse genes and to functionally analyze them through a genetic approach. Null mutant mice will be created and their phenotype will be histologically and molecularly characterized. In addition, misexpression of the new genes in transgenic mice will be analyzed.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
76021 KARLSRUHE
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.