Objective
Research objectives and content
The luteinizing hormone-releasing hormone (LHRH) neurones of the brain control reproductive cycles in the female. Although estrogen, secreted by the ovaries, exerts an important influence on LHRH neurones it is not known how this occurs in any species. The objectives of this project are to:
1) Define the neurones expressing estrogen receptors which are likely to project to the LHRH neurones of the ewe 2) Determine the neurotransmitters being used by these neurones, and 3) Establish the effects of estrogen on neurotransmitter synthesis in these cells. The project will involve the use of retrograde tracing techniques, double- and triple- labelling immunocytochemistry to achieve 1) and 2), and in situ hybridization for the analysis of specific neurotransmitter-related messenger RNAs in the brain of the ewe
Training content (objective, benefit and expected impact)
The objective of my proposed post-doctoral study at The Babraham Institute will be to provide myself with a solid grounding in 'state-of-the-art' neuroanatomical and cellular messenger RNA techniques. This will complement my present skills regarding in vivo neurobiological assessment and is critical if I am to obtain the global training now required within the field of neurobiology. A successful post-doctoral period in Dr Herbison's laboratory should greatly enhance my chances of acquiring a University position in France.
Links with industry / industrial relevance (22)
I understand that there are no present links with industry which concern this application.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
CB2 4AT Cambridge
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.