Objective
Research objectives and content
Rhodobacter sphaeroides is a motile, facultative phototrophic bacterium able to sense and respond to several stimuli (light, oxygen, nutrients, repellents). This is the first species in which multiple chemosensory pathways, responsible of a balanced response to an ever-changing environment, have been identified. The main research objectives are: to identify the receptor sensing changes in the rate of electron transport induced by light, oxygen and naerobic electron acceptor, compare this to other redox sensor and analyse the interactions with the electron transport chain; to establish which of the cytoplasmic chemosensory pathways is involved; how these different signals are integrated; to investigate how the swimming behaviour is modified by this sensory signal. The project will involve molecular biology techniques (gene cloning and sequencing, PCR amplification, mutagenesis, analysis and control of gene expression); protein chemistry; redox spectroscopy;kinetic measurements; computerised motion analysis.
Training content (objective, benefit and expected impact)
This project will allow me to learn a full range of molecular techniques and provide the unique opportunity to integrate these with biophysical analysis and computer modelling. It will be the first description of integration of redox sensing and chemosensing in a non-enteric species and allow modelling of the effects of different, conflicting gradients on the behaviour of bacterial populations in the environment.
Links with industry / industrial relevance (22)
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences computer and information sciences artificial intelligence computer vision motion analysis
- natural sciences physical sciences optics spectroscopy
- natural sciences biological sciences molecular biology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
OX1 3QU OXFORD
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.