CORDIS
EU research results

CORDIS

English EN
Precision engineering of plant genes

Precision engineering of plant genes

Objective

The quality of transgene expression is influenced by the position of integration in the genome and the complexity of the integrated DNA. Today' s methods cannot control both parameters, but gene targeting would be the solution. However, this technology is not available in higher plants. Gene targeting relies on homologous recombination. Progress in the general understanding of homologous recombination and the discovery of highly efficient gene targeting in a moss allow new approaches to improve gene targeting in plants. Key parameters that differ in efficient and inefficient systems are analysed, appropriate genes and/or features transferred to low efficiency gene-targeting systems and the function are confirmed in the modified systems. Concepts shown to improve gene targeting are transferred to commercially important systems as a first step towards application.

Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

Address

Carl-Von-LinnÉ-Weg 10
50829 Koeln

Germany

Administrative Contact

Egon KRUECK (Mr)

Participants (7)

Sort alphabetically

Expand all

BASF PLANT SCIENCE GMBH

Germany

CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS

Spain

SUNGENE GMBH & CO. KGAA

Germany

UNIVERSITY OF GENEVA

Switzerland

UNIVERSITY OF LAUSANE

Switzerland

UNIVERSITY OF LEEDS

United Kingdom

WAGENINGEN UNIVERSITY

Netherlands

Project information

Grant agreement ID: QLK3-CT-2000-00365

  • Start date

    1 March 2001

  • End date

    30 June 2004

Funded under:

FP5-LIFE QUALITY

  • Overall budget:

    € 2 849 882

  • EU contribution

    € 1 836 153

Coordinated by:

MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

Germany