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Novel gene drug strategy based on hybridisation of functional entities to plasmids.

Objectif

Gene therapy is an emerging technology with the potential of having an important impact on future treatments of human diseases. Efficient gene transfer relies on optimal receptor binding, intracellular vesicular transport and nuclear uptake. According to these requirements, a novel GENE DRUG therapeutic strategy will be developed. This strategy is asked on a patented plastid delivery system in which functional entities, improving delivery efficiency, are attached to the plastid by means of hybridisation. The proposal is focused on the delivery of therapeutic genes for cardiovascular diseases and haemophilia.

Appel à propositions

Data not available

Régime de financement

CSC - Cost-sharing contracts

Coordinateur

KAROLINSKA INSTITUTE
Contribution de l’UE
Aucune donnée
Adresse
Solnavagen 1
171 77 STOCKHOLM
Suède

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Coût total
Aucune donnée

Participants (3)