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CORDIS

Novel gene drug strategy based on hybridisation of functional entities to plasmids.

Ziel

Gene therapy is an emerging technology with the potential of having an important impact on future treatments of human diseases. Efficient gene transfer relies on optimal receptor binding, intracellular vesicular transport and nuclear uptake. According to these requirements, a novel GENE DRUG therapeutic strategy will be developed. This strategy is asked on a patented plastid delivery system in which functional entities, improving delivery efficiency, are attached to the plastid by means of hybridisation. The proposal is focused on the delivery of therapeutic genes for cardiovascular diseases and haemophilia.

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KAROLINSKA INSTITUTE
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171 77 STOCKHOLM
Schweden

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