Objective
Protein-Protein interactions are fundamental to biology and constitute an interesting target class for medicinal chemistry projects investigating cell adhesion, signal transduction, proteolysis or protein folding diseases. With the deciphering of the human genome project, the next decades will bring a myriad of new proteins being potentially important receptors since they might be associated with diseases. To design ligands towards such receptors, peptides and peptidomimetics will play an important role, since they are known to display unprecedented structural and functional diversity. One challenging aspect of peptidomimetic chemistry is to develop a strategy, which results in molecules that adopt specific secondary structures relevant to those found in protein segments or substrate-bound peptides of interest. Despite numerous efforts, there are today only few success stories where chemists have redirected the complex nature of protein-protein interactions. So an important step in this effort is the development of molecular scaffold inducing conformational constraints.
The research topic of the early stage research projects proposed by this network is to design, synthetise, characterise the secondary structure of new peptidomimetics of biological interest and finally to evaluate their biological activities. The aim of the present project is to build a model of training program in medicinal chemistry in order to create a very stimulating, international and interdisciplinary environment for the training of young res earchers at the early stage of their scientific career. The project gathers three academic groups with excellent expertise in various areas of chemical and medicinal chemical sciences: 1) Università dell'lnsubria - ltaly; 2) Université de Paris Sud - France ; 3) University of Regensburg -Germany. A training programme will be set, based on common PhD projects (vide infra) between the partners, in order to foster mobility of young researchers.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- natural sciences biological sciences cell biology
- natural sciences biological sciences biochemistry biomolecules proteins protein folding
- natural sciences chemical sciences organic chemistry amines
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-2
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
VARESE
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.