Objective
The MAPKINASE project aims to elucidate aspects of the mode of action of the important plant growth substance ethylene by integrating genetic, biochemical and proteomic approaches, hence capitalising on the post-genomic advantages of Arabidopsis as a model system. The scientific objectives are two-fold. Firstly, to define the ethylene-modulated phosphorylome and secondly to model phosphorylation flux in ethylene-mediated MAPkinase cascades. The work will use tissue from wild type treated with or without et hylene and will also study the ctr1-1 mutant where the lesion is in a MAP3kinase gene, (phenotype is constitutively "ethylene-treated") and where the relevant cascades are switched on. The work will deploy advanced techniques in proteomics including two-dimensional electrophoresis and differential staining with fluorescent dyes to identify differences with treatment, together with a range of mass-spectroscopies for identification, combined with advances bioinformatics. The outcomes will result in a much d eeper understanding of the processes of signal transduction. The proposal responds to the need to bring to the research project, the top class scientific expertise of the proposed Fellow whilst also providing opportunites for continuing professional develo pment including access to an independent professional mentor and training courses in ethical and financial management. The broader objectives include training in a number of relevant scientific and complementary skills including developments in protein p urification separation and detection, robot-technology, mass spectrometries and statistical analyses of proteome data-sets. The research, in support of the Lisbon and Gothenburg objectives, will not only contribute to the developing knowledge-based economy but will aid the development of genuinely effective and working relationshiops with Russia. The project fully supports the mobility agenda of the ERA to encourage the spread of knowledge within Europe.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- natural sciences chemical sciences electrochemistry electrophoresis
- natural sciences chemical sciences organic chemistry aliphatic compounds
- natural sciences chemical sciences analytical chemistry mass spectrometry
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-MOBILITY-7
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
IIF - Marie Curie actions-Incoming International Fellowships
Coordinator
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.