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Arabidopsis growth network integrating OMICS technologies

Objective

Plants are crucial to mankind as they supply food, chemicals, pharmaceuticals and renewable resources. Yet the processes by which they grow are poorly understood. Although some of the key factors involved in plant organ growth have already been identified, the circuitry that links the different levels of organisation (whole plant, organ, cell, molecular module, molecule) remains to be uncovered. Fortunately, for the first time, techniques exist or can be developed to characterise a multicellular system exhaustively at all relevant levels.

The main goals of AGRON-OMICS are
- to survey systematically with an array of high throughput methods what are the molecular components driving growth in the cells of a developing Arabidopsis leaf,
- to understand how these elements interact and coordinate their action across levels of organisation, and
- to explain quantitative growth phenotypes at the molecular level through inference and mathematical MODELLING, followed by further laboratory validation.

The partnership tackling these ambitious goals has two poles: BIOLOGY, the laboratories involved study the main known molecular pathways that regulate and implement leaf growth, including cell cycle, cell wall biosynthesis and remodelling, carbon and nitrogen metabolism, and photosynthesis; TECHNOLOGY, each of them offers a unique platform chosen to record variables describing Arabidopsis plant and growth, from the macroscopic analysis of leaf size and shape, to the in depth analysis of molecular cell components.

AGRON-OMICS will establish the infrastructure necessary to organise its multidisciplinary research programme, then to integrate and interpret a wide range of data sets. With a strong emphasis on DISSEMINATION, this project will create knowledge used in industrial applications and will yield data, tools, resources and novel technologies that will be released to the research community at large as soon as practically feasible.

Call for proposal

FP6-2005-LIFESCIHEALTH-6
See other projects for this call

Funding Scheme

IP - Integrated Project

Coordinator

FLANDERS INTERUNIVERSITY INSTITUTE FOR BIOTECHNOLOGY
Address
Rijvisschestraat 120
Ghent
Belgium

Participants (9)

INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE
France
Address
147, Rue De L'universite'
Paris
MAX PLANCK SOCIETY FOR THE ADVANCEMENT OF SCIENCE
Germany
Address
Hofgartenstrave 8
D-80084 Munich
EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH
Switzerland
Address
Raemistrasse 101
Zurich
JOHN INNES CENTRE
United Kingdom
Address
Norwich Research Park, Colney
Norwich
UNIVERSITY OF WARWICK
United Kingdom
Address
Gibbet Hill Road
Coventry
THE UNIVERSITY OF NOTTINGHAM
United Kingdom
Address
University Park
Nottingham
STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK
Netherlands
Address
Costerweg 50
9101 Wageningen
UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE
Spain
Address
Avenida De La Universidad S/n
---- Elche
MAIA SCIENTIFIC NV
Belgium
Address
Cipalstraat 3
Geel