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Genetic factors influencing disease susceptibility in cultured fish

Objective

The project aims to identify genetic characters involved in the relationship between fish host and pathogens. Both are involved in determining the susceptibility of fish to disease and genetic information will provide valuable tools for management control and prevention of disease. By comparing the nucleic acid of pathogenic and non-pathogenic forms of pathogen (e.g. parasite species. virus strains) and that of infected and control fish. genetic factors specific to pathogenic forms and resistant or susceptible strains of Fish will be identified.

These can then be used as markers for potentially. dangerous strains of pathogen or vulnerable lines of fish. Virus and parasite genes known to contain species and strain variation will be analysed by sequencing and mutation scanning methods. Fish gene expression will be analysed by differential display methods to identify variations between infected and uninfected individuals. The full-length genes will be obtained and gene function predicted or identified.

Topic(s)

Data not available

Funding Scheme

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Coordinator

University of Aberdeen
EU contribution
No data
Address
2 Tillydrone Avenue
AB9 2TN Aberdeen
United Kingdom

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Total cost
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