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Content archived on 2024-06-18

DEVELOPMENT AND APPLICATIONS OF NEW YLID CHEMISTRY

Objective

The aims of this research are to develop efficient synthetic methodology for one-pot catalytic cross-metathesis/tandem oxonium ylide formation– [2,3] sigmatropic rearrangement of unsaturated diazocarbonyl substrates, to establish a pool of useful chiral catalysts for this chemistry, and to apply this methodology in strategies for the enantioselective synthesis of selected biologically active natural product classes. The objectives are: Development and scope of one-pot cross-metathesis/tandem oxonium ylide formation– [2,3] sigmatropic rearrangement New catalyst preparation and evaluation in enantioselective tandem ylide formation – rearrangement Development of asymmetric synthesis strategies to hyperolactone anti-HIV agents

Fields of science (EuroSciVoc)

Keywords

Topic(s)

Call for proposal

FP7-PEOPLE-IEF-2008
See other projects for this call

Funding Scheme

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
EU contribution
€ 171 867,63
Address
WELLINGTON SQUARE UNIVERSITY OFFICES
OX1 2JD Oxford
United Kingdom
Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
Links
Total cost
No data