Objective
Within the last years, the ribonucleoprotein telomerase has emerged as an attractive, yet elusive, drug target for the treatment of cancer and several age-related diseases. This is because it has been estimated that telomerase is abnormally up-regulated in around 90% of human tumors. However, despite the current efforts to exploit the therapeutic potential of telomerase, there is still a need for the development of alternative chemical strategies that may unravel novel options for efficient therapeutic intervention, especially at a time when our understanding of many aspects of telomerase biology is ever increasing. The proposed research aims at the use of new molecular strategies for the discovery of efficient telomerase inhibitors based on oligonucleotide conjugates. The project will be based on an interfaced, multidisciplinary approach characteristic of the field of Chemical Biology. It will entail a combination of different techniques, including organic synthesis, coordination and nucleoside chemistry, spectroscopy, biochemistry, and molecular and cellular biology.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry
- medical and health sciences clinical medicine oncology
- natural sciences physical sciences optics spectroscopy
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2009-RG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
28801 Alcala De Henares/Madrid
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.