Objectif Galanthamine is an alkaloid produced exclusively by plants of the family Amaryllidaceae, mainly belonging to the genus Galanthus, Leucojum and Narcissus. Owing to its acetylcholinesterase inhibitory activity, galanthamine is used and marketed for the treatment of the Alzheimer’s disease, among others. Although it is obtained by organic synthesis, galanthamine is also being extracted from natural sources. Both Galanthus and Leucojum plants are very widespread in the Eastern European countries, whereas Narcissus plants are mainly distributed in the Mediterranean region. For industrial purposes, Leucojum aestivum plants are gathered from wild populations in their natural habitat, which causes increasing problems regarding quality of the plant material as well as depletion pressure on the natural populations of L. aestivum. By development of an in vitro production method, both problems will be overcome. Narcissus confusus, an endemic species growing in Spain, was found to produce around two-fold higher amount of galanthamine than L. aestivum. Both plant species will also be propagated and subjected to further agronomic studies for the initiation of new crops of highly galanthamine-containing plants. Integrating both research approaches, the initiation of new crops of L. aestivum and N. confusus and the establishment of the in vitro production method, will result in the development of a sustainable production method of galanthamine. Since galanthamine in Europe is produced by highly specialised SMEs, significant improvement in this field can only be achieved by cooperation on European level. The co-operative research implemented in the SUPROGAL project will thus markedly improve the competitiveness of the involved SMEs. Champ scientifique medical and health sciencesbasic medicineneurologydementiaalzheimeragricultural sciencesagriculture, forestry, and fisheriesagriculturesocial scienceseconomics and businesseconomicssustainable economy Programme(s) FP7-SME - Specific Programme "Capacities": Research for the benefit of SMEs Thème(s) SME-1 - Research for SMEs Appel à propositions FP7-SME-2007-1 Voir d’autres projets de cet appel Régime de financement BSG-SME - Research for SMEs Coordinateur UNIVERSITAT DE BARCELONA Contribution de l’UE Aucune donnée Adresse GRAN VIA DE LES CORTS CATALANES 585 08007 Barcelona Espagne Voir sur la carte Région Este Cataluña Barcelona Type d’activité Higher or Secondary Education Establishments Contact administratif Carles Codina (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Participants (6) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire BULPHYTOOILS JOINTSTOCK COMPANY BPHO Bulgarie Contribution de l’UE € 152 240,00 Adresse Tvardishki Prohod Street 23 Office 4 1404 Sofia Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Dimitar Shopov (Mr.) Liens Contacter l’organisation Opens in new window Coût total Aucune donnée VITROFLORA Laboratorium Kultur Tkankowych Pologne Contribution de l’UE € 232 815,00 Adresse UL. BUKOWA 3 86 065 LOCHOWO Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Anna Pawlak (Mrs.) Liens Contacter l’organisation Opens in new window Coût total Aucune donnée BV AMARYLLIS KWEEKERIJ LUDWIG & CO Pays-Bas Contribution de l’UE € 221 980,00 Adresse MIDDENWEG 13 2161 LR LISSE Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Rudolf Berbee (Mr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée AGROBIOINSTITUTE Bulgarie Contribution de l’UE Aucune donnée Adresse Bul. Dragan Tzankov 8 1164 Sofia Voir sur la carte Région Югозападна и Южна централна България Югозападен София Type d’activité Research Organisations Contact administratif Violeta Kondakova (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée BIOPLANTA GmbH Allemagne Contribution de l’UE Aucune donnée Adresse Deutscher Platz 5 04103 Leipzig Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Dirk Wilken (Dr.) Liens Contacter l’organisation Opens in new window Coût total Aucune donnée Holland Biodiversity B.V. Pays-Bas Contribution de l’UE € 180 125,00 Adresse Middenweg 13 2161 LR Lisse Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Diane Bentvelzen (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée
