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Genetic Improvement of Algae for Value Added Products

Objective

Microalgae are a highly promising resource for the sustainable production of a wide variety of biomaterials for a wide range of applications. Microalgae can transform solar energy at high efficiency directly into valuable biological products using marginal water resources, waste nutrients and exhaust CO2 without the needs for high value cropland. A wide variety of eukaryotic microalgae of high evolutionary diversity produce naturally valuable products like polyunsaturated fatty acids, carotenoids, medically active carbohydrates etc. Nevertheless only a few commercially viable algal products have entered the market. Algal cultivation and induction of high value product accumulation is a complex problem, algae grow in diluted solutions and require large areas and water volumes, causing high cultivation and harvesting costs and posing contamination problems and variable productivities due to climate variability. Genetic modifications to make microalgae better suit industrial applications are possible over a wide range of target mechanisms: stress tolerance, product accumulation pathways, cellular chlorophyll contents, novel metabolic pathways, resistance to pathogens and competition, etc. Due to the wide variability of algal strains under consideration, available techniques for genetic manipulations have to be adapted or developed for all algal strains of interest. Our consortium will adapt genetic engineering techniques to various algal strains of economic interest focusing on carotenoid and PUFA production and the overexpression of peptides of commercial value. In parallel we will develop cultivation technologies, harvesting and extraction methods for lipids, carotenoids and proteins using existing model algae strains that will then be adapted to suitable improved strains. Furthermore products will be tested for energy, pharmaceutical, nutritional or medical applications for economic evaluation of the production processes and their economic exploitation.

Call for proposal

FP7-KBBE-2010-4
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Coordinator

BEN-GURION UNIVERSITY OF THE NEGEV
Address
.
84105 Beer Sheva
Israel

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Schneider Dori (Ms.)
EU contribution
€ 699 719,25

Participants (13)

ROTHAMSTED RESEARCH LTD
United Kingdom
EU contribution
€ 520 181,75
Address
Harpenden
AL5 2JQ Herts

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Activity type
Other
Administrative Contact
Dominique Imber (Ms.)
JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
Germany
EU contribution
€ 402 879,60
Address
Theodor W Adorno Platz 1
60323 Frankfurt Am Main

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Schmitt Mareike (Ms.)
GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS
Germany
EU contribution
€ 466 200
Address
Wilhelmsplatz 1
37073 Gottingen

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Nadja Daghbouche (Ms.)
UCL Elizabeth Garrett Anderson Institute for Women’s Health
United Kingdom
EU contribution
€ 527 416
Address
Gower Street
WC1E 6BT London

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Greta Borg-Carbott (Ms.)
A4F ALGAFUEL SA
Portugal
EU contribution
€ 400 550
Address
Estrada Do Paco Do Lumiar Campus Do Lumiar Edificio E R/c
1649 038 Lisboa

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Teresa Alvarez (Ms.)
ROSETTA GENOMICS LTD

Participation ended

Israel
Address
Plaut Street 10
76706 Rehovot
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Limor Stoller (Ms.)
UNIVERSITE DU MANS
France
EU contribution
€ 487 730
Address
Avenue Olivier Messiaen
72085 Le Mans

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Claire Philippe (Ms.)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
EU contribution
€ 593 520
Address
Rue Michel Ange 3
75794 Paris

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Activity type
Research Organisations
Administrative Contact
Ludovic Hamon (Mr.)
UNIVERSITA DEGLI STUDI DI FIRENZE
Italy
EU contribution
€ 487 682,40
Address
Piazza San Marco 4
50121 Florence

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Luciana Giovannetti (Prof.)
ALGATECHNOLOGIES (1998) LTD
Israel
EU contribution
€ 392 560
Address
Kibbutz Ketura
88840 D.n. Eilot

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Oran Ayalon (Dr.)
Nimrod Shaham & Amos Zamir Certified Public Accountants
Israel
EU contribution
€ 120 000
Address
Shapira 16
52506 Ramat Gan

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Nimrod Shaham (Mr.)
ROSETTA GREEN LTD

Participation ended

Israel
EU contribution
€ 412 898,40
Address
Plaut St 10
76706 Rehovot
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Limor Stoller (Ms.)
A B SEEDS LTD
Israel
EU contribution
€ 85 269,60
Address
Gad Feinstein 13
76121 Rehovot

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Limor Zur-Stoller (Mrs.)