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Global Research in Paediatrics

Objective

Paediatric drugs (PD) lack appropriate testing. Most drugs have inadequate information about dosing regimen, dose adjustment and how to administer them. These are longstanding problems that unquestionably require concerted efforts at the international level. Both the US and the EU have introduced paediatric legislation that facilitates participation of children in research and pharmaceutical innovation but initiatives are not always coordinated and often different approaches are used to deal with the same problems. The main aim of GRiP will be to implement an infrastructure matrix to stimulate and facilitate the development and safe use of medicine in children. This implementation entails active coordination of knowledge management efforts and integrated use of existing research capacity, whilst reducing the fragmentation and duplication of activities. The consortium will primarily focus on: 1) development of a Paediatric Clinical Pharmacology Training Program; 2) Validation and harmonisation of research tools specific for paediatrics; 3) Sharing of strategies and plans; 4) Use of ongoing/planned research studies to evaluate the feasibility of proposed research tools and strategies. GRiP brings together an exceptional range of high quality leaders and stakeholders that are very active in the context of EU and US paediatric medicines research. GRiP will mobilize 21 institutions as partners and at least another 16 major networks that represent several hundreds of clinical sites and a total of more than 1000 researchers across Europe, the US and Asia. The integration of the WHO, EMA and the NIH-NICHD associated networks, including the FDA, will be a major asset not just for an effective implementation of the network activities without duplication, but also for the rapid translation of GRiP deliverables into practice. This partnership will work closely with families to provide children with safe and effective medicines.
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Coordinator

AZIENDA OSPEDALIERA DI PADOVA

Address

Via Giustiniani 1
35128 Padova

Italy

Activity type

Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)

EU Contribution

€ 335 297,75

Administrative Contact

Carlo Giaquinto (Prof.)

Participants (22)

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THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON

United Kingdom

United States Department of Health and Human Services

United States

THE EUROPEAN MEDICINES AGENCY

United Kingdom

EU Contribution

€ 150 900

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Netherlands

EU Contribution

€ 1 135 134

THE UNIVERSITY OF LIVERPOOL

United Kingdom

EU Contribution

€ 725 688

OSPEDALE PEDIATRICO BAMBINO GESU

Italy

EU Contribution

€ 721 932

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

EU Contribution

€ 558 941,82

National Center for Child Health and Development

Japan

EU Contribution

€ 83 642

ST GEORGE'S HOSPITAL MEDICAL SCHOOL

United Kingdom

EU Contribution

€ 314 332

CONSORZIO PER VALUTAZIONI BIOLOGICHE E FARMACOLOGICHE

Italy

EU Contribution

€ 1 057 721,25

UNIVERSITEIT LEIDEN

Netherlands

EU Contribution

€ 222 169,98

ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM

Netherlands

EU Contribution

€ 235 288

FUNDACION VASCA DE INNOVACION E INVESTIGACION SANITARIAS

Spain

EU Contribution

€ 408 304,63

INSTYTUT POMNIK CENTRUM ZDROWIA DZIECKA

Poland

EU Contribution

€ 145 601,94

WORLD HEALTH ORGANIZATION

Switzerland

EU Contribution

€ 99 357

UNIVERSITY COLLEGE LONDON

United Kingdom

EU Contribution

€ 586 728,88

HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ

Finland

EU Contribution

€ 788 560

BRIGHTON COLLABORATION FOUNDATION

Switzerland

EU Contribution

€ 602 997

FONDAZIONE PENTA-FOR THE TREATMENT AND CARE OF CHILDREN WITH HIV-ONLUS

Italy

EU Contribution

€ 1 022 792

VERENIGING SAMENWERKENDE OUDER- EN PATIENTENORGANISATIES

Netherlands

EU Contribution

€ 123 750

The Hospital for Sick Children

Canada

EU Contribution

€ 578 100,01

UNIVERSITE PARIS DIDEROT - PARIS 7

France

EU Contribution

€ 102 761,53

Project information

Grant agreement ID: 261060

Status

Closed project

  • Start date

    1 January 2011

  • End date

    30 June 2017

Funded under:

FP7-HEALTH

  • Overall budget:

    € 12 637 322,83

  • EU contribution

    € 9 999 999,79

Coordinated by:

AZIENDA OSPEDALIERA DI PADOVA

Italy