Objetivo Lung and pancreatic cancers still have a mortality rate over 85% at 5 years of diagnosis, a clear demonstration of the actual treatment failure and the need for improved clinical management. This involves better tools for diagnosis, prognosis, and selection of sensitive and resistant patients to current conventional therapies or improved innovative treatments as well as the development of novel therapeutic strategies.The major objective of this proposal is to improve management of patients with either lung or pancreatic tumors by studying the clinical applications of still not investigated metabolic and signalling pathways with the following aims:-development of new tools for early diagnosis-identification of novel tumour markers for early diagnosis and prognosis-prediction of response to conventional treatments-identification of the molecular mechanisms of generation of resistance-development of improved treatments based on the identification of novel molecular targets-design of novel anticancer strategies.-achieve a better understanding of how combinatorial treatments using current standard clinical procedures with novel treatments under development may improve patient outcome.The proposed consortium is composed of four experimental research groups with a profound knowledge on molecular and cellular biology of cancer, and ample experience in the design of targeted and personalized cancer therapies along with translational research, complemented with three clinical groups with an extensive experience in the clinical management of lung and pancreatic cancer patients, guaranteeing a clinical proof-of principle and applicability, integrating basic-clinical European scientific excellence. Furthermore, the consortium has incorporated one company with direct involvement in critical areas that will make feasible to translate to the clinic the results generated in the project. Ámbito científico social sciencessociologydemographymortalitymedical and health sciencesclinical medicineoncologypancreatic cancer Programa(s) FP7-HEALTH - Specific Programme "Cooperation": Health Tema(s) HEALTH.2010.2.4.1-6 - Translational research on cancers with poor prognosis. FP7-HEALTH-2010-two-stage Convocatoria de propuestas FP7-HEALTH-2010-two-stage Consulte otros proyectos de esta convocatoria Régimen de financiación CP-FP - Small or medium-scale focused research project Coordinador FUNDACION SECTOR PUBLICO ESTATAL CENTRO NACIONAL INVESTIGACIONES ONCOLOGICAS CARLOS III Aportación de la UE € 1 567 092,80 Dirección C MELCHOR FERNANDEZ ALMAGRO 3 28029 Madrid España Ver en el mapa Región Comunidad de Madrid Comunidad de Madrid Madrid Tipo de actividad Research Organisations Contacto administrativo Dolores Liebanes (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Participantes (6) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo THE UNIVERSITY OF LIVERPOOL Reino Unido Aportación de la UE € 206 250,00 Dirección BROWNLOW HILL 765 FOUNDATION BUILDING L69 7ZX Liverpool Ver en el mapa Región North West (England) Merseyside Liverpool Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Veronica Shaw (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Reino Unido Aportación de la UE € 439 754,00 Dirección SOUTH KENSINGTON CAMPUS EXHIBITION ROAD SW7 2AZ LONDON Ver en el mapa Región London Inner London — West Westminster Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Eric Aboagye (Prof.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos THORAXKLINIK HEIDELBERG GEMEINNUTZIGE GEM GMBH Alemania Aportación de la UE € 254 250,00 Dirección AMALIENSTRASSE 5 69126 HEIDELBERG Ver en el mapa Tipo de actividad Research Organisations Contacto administrativo Thomas Muley (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos SERVICIO MADRILENO DE SALUD España Aportación de la UE € 183 902,00 Dirección Paseo De la Castellana, 280 28046 MADRID Ver en el mapa Región Comunidad de Madrid Comunidad de Madrid Madrid Tipo de actividad Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Contacto administrativo José Ignacio Flores Nicolás (Mr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos KATHOLIEKE UNIVERSITEIT LEUVEN Bélgica Aportación de la UE € 164 600,00 Dirección OUDE MARKT 13 3000 Leuven Ver en el mapa Región Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Elke Lammertyn (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos GE HEALTHCARE LIMITED Reino Unido Aportación de la UE € 180 960,00 Dirección POLLARDS WOOD NIGHTINGALES LANE HP8 4SP CHALFONT ST GILES Ver en el mapa Región South East (England) Berkshire, Buckinghamshire and Oxfordshire Buckinghamshire CC Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Sajinder Luthra (Dr.) Enlaces Contactar con la organización Opens in new window Coste total Sin datos