Project description
Revolutionising structural biology for viral defence
Recent viral threats underscore the urgency to confront emerging viruses with enhanced preparedness. A deeper understanding of the dynamic intricacies of viral structures is key. At the crossroads of viral evolution and medical response, a pivotal challenge arises: the need of expertise spanning theoretical understanding, instrument development, and application in the realm of structural biology for protein-drug interactions. In this context, the MSCA-funded SPIDoc’s project aims to enhance our understanding of viral structures. Merging mass spectrometry with light sources will offer unprecedented insights through X-ray based single particle imaging (SPI), among other approaches. Overall, the goal is to train a new generation of scientists, and pioneer data management standards.
Objective
SPIDoc’s DN stems from the need to prepare for emerging viruses enabling a fast response, as became evident lately. Basically, better knowledge of the dynamic nature of viral structures is required and fundamental to combat with appropriate treatments. In this perspective, several technologies were developed for structural biology, including a cutting-edge approach combining mass spectrometry (MS) and X-rays for single particle imaging (SPI) in MS SPIDOC. Despite these advances, a major bottleneck that the scientific community will face in coming years will be the lack of expertise with a broad knowledge from theory, instrument development and application relevant to structural biology with MS.
SPIDoc’s therefore aims to train the next generation of scientists with such expertise by a dedicated intersectoral training programme. SPIDoc’s projects are highly interlinked and the proposed training programme aims to provide the doctoral candidates with the basic and advanced knowledge to build a common interdisciplinary language, to work in teams and to acquire deep knowledge by a combination of lectures and practical sessions. An important aspect will be given to data management and the establishment of currently lacking standards for native MS metadata.
The research training is complemented by transferrable skills courses, setting the basis for progressing through the doctoral studies as well as for future career progression. Within these modules, training on equal opportunities and unconscious bias are included, shaping the future generation towards creating fair workplaces. Special attention will be paid to green-practice measures from the everyday practice in laboratories and offices up to the institutional level. By including developments from computational theory to instrumentation, the SPIDoc’s beneficiaries and associated partners will closely work together to advance cutting-edge technologies and apply them towards fast response.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-DN-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
23562 Lubeck
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.