The effect of a sedentary lifestyle on type 2 diabetes and its complications

Objective

Low physical activity is a well-known risk factor of many healthy problems. It is, however, not clear whether the increased health risks are due to lack of moderate to vigorous activity or due to a more sedentary lifestyle. Sedentary behaviour cannot simply be defined as the lack of moderate to vigorous activity but is defined as engaging in activities which marginally increase energy expenditure above resting level such as sitting, using the computer, and watching television. Understanding the health consequences of sedentary behaviour independently and jointly associated with physical activity is essential in order to promote healthy behaviours and more effective guidelines.

In the present proposal we aim to disentangle the relation between objectively measured sedentary behaviour and physical activity in relation to type 2 diabetes and diabetic complications in the Maastricht Study in the Netherlands. The Maastricht Study is a large newly established cohort study focusing on the determinants and consequences of type 2 diabetes. Using the innovative activPAL™ accelerometer we will be able to examine daily activity across the full range of activity intensities. The objectives of the current proposal are:
1) to describe and compare patterns of daily activity among people with diabetes, prediabetes and those without type 2 diabetes;
2) to examine the association between sedentary behaviour and prevalent and incident (pre)diabetes and to understand whether this is independent of physical activity; and
3) to examine the relation between sedentary behaviour and prevalent and incident diabetic complications and to understand whether this is independent of physical activity.

This research will both advance the physical activity research field and the diabetes field. The discoveries of the project are expected to have important public health impact and can affect both physical activity guidelines and guidelines to prevent/delay type 2 diabetes and its complications.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

• medical and health sciences health sciences public health
• medical and health sciences clinical medicine endocrinology diabetes

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

• FP7-PEOPLE-2011-CIG - Marie-Curie Action: "Career Integration Grants"

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2011-CIG
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-CIG - Support for training and career development of researcher (CIG)

Coordinator