Institut Curie 3-i PhD Program

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Periodic report on dissemination activities 2

The report on dissemination activities should contain at least the following information Dates of Call Publication and places where it was published Flyers brochures or other information produced Presentations conferences and meetings or other events Published articles in the press Any other means of advertising the programme

Periodic report on dissemination activities 1

The report on dissemination activities should contain at least: - Dates of Call Publication and places where it was published (Supporting documents required). - Flyers, brochures, or other information produced - Presentations conferences and meetings or other events - Published articles in the press - Any other means of advertising the programme

Publicaciones

Stem Cell DNA Damage and Genome Mutation in the Context of Aging and Cancer Initiation

Autores: Lara Al-Zouabi and Alison Bardin
Publicado en: Cold Spring Harbor Perspectives in Biology, 2020, Página(s) -, ISSN 1943-0264
Editor: Cold Spring Harbor Laboratory Press
DOI: 10.1101/cshperspect.a036210

Multiscale morphogenesis of the mouse blastocyst by actomyosin contractility.

Autores: Özge Özgüç; Jean-Léon Maître
Publicado en: Current Opinion in Cell Biology, Edición Volume 66, 2020, Página(s) 123-129, ISSN 0955-0674
Editor: Elsevier BV
DOI: 10.1016/j.ceb.2020.05.002

BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation.

Autores: Campagne, Antoine; Lee, Ming-Kang; Zielinski, Dina; Michaud, Audrey; Le Corre, Stéphanie; Dingli, Florent; Chen, Hong; Shahidian, Lara Z.; Vassilev, Ivaylo; Servant, Nicolas; Loew, Damarys; Pasmant, Eric; Postel-Vinay, Sophie; Wassef, Michel; Margueron, Raphaël
Publicado en: Nature Communications, Edición 10, 2019, Página(s) pp.348, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-018-08255-x

Recent advances towards deciphering human dendritic cell development

Autores: Javiera Villar, Elodie Segura
Publicado en: Molecular Immunology, Edición Volume 122, 2020, Página(s) Pages 109-115, ISSN 0161-5890
Editor: Pergamon Press
DOI: 10.1016/j.molimm.2020.04.004

Synthetic reconstruction of the hunchback promoter specifies the role of Bicoid, Zelda and Hunchback in the dynamics of its transcription

Autores: Huy Tran; Gonçalo Fernandes; Maxime Andrieu; Youssoupha Diaw; Carmina Perez Romero; Cécile Fradin; Mathieu Coppey; Aleksandra M Walczak; Nathalie Dostatni
Publicado en: eLife, 2022, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.74509

Transcription factor EB regulates phosphatidylinositol-3-phosphate levels that control lysosome positioning in the bladder cancer model

Autores: Mathur, P., De Barros Santos, C., Lachuer, H. et al.
Publicado en: Commun Biol, Edición 6, 2022, Página(s) 114, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s42003-023-04501-1

The human pre-replication complex is an open complex

Autores: Jian Li, Jiangqing Dong, Weitao Wang, Daqi Yu, Xinyu Fan, et al.
Publicado en: Cell, Edición 186 (1), 2022, Página(s) 98-111, ISSN 0092-8674
Editor: Cell Press
DOI: 10.1016/j.cell.2022.12.008

Review of Experimental Studies to Improve Radiotherapy Response in Bladder Cancer: Comments and Perspectives

Autores: Linda Silina, Fatlinda Maksut,Isabelle Bernard-Pierrot,François Radvanyi,Gilles Créhange,Frédérique Mégnin-Chanet and Pierre Verrelle
Publicado en: Cancers, Edición 13(1), 2021, Página(s) 87, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13010087

Acridine–O6-benzylguanine hybrids: Synthesis, DNA binding, MGMT inhibition and antiproliferative activity

Autores: Jaime Franco Pinto, Alexandra Fillion, Patricia Duchambon, Sophie Bombard, Anton Granzhan
Publicado en: European Journal of Medicinal Chemistry, Edición Volume 227, 2022, Página(s) 11390, ISSN 0223-5234
Editor: Elsevier BV
DOI: 10.1016/j.ejmech.2021.113909

Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86

Autores: Haiyin Liu, Kayla R Wilson, Ashley M Firth, Christophe Macri, Patrick Schriek, Annabelle B Blum, Javiera Villar, Samuel Wormald, Mitch Shambrook, Bangyan Xu, Hui Jing Lim, Hamish E G McWilliam, Andrew F Hill, Laura E Edgington-Mitchell , Irina Caminschi , Mireille H Lahoud, Elodie Segura, Marco J Herold, Jose A Villadangos, Justine D Mintern
Publicado en: Nature Communications, Edición 13, 2022, Página(s) 1934, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-29524-w

Stiffness and tension gradients of the hair cell’s tip-link complex in the mammalian cochlea

Autores: Mélanie Tobin, Atitheb Chaiyasitdhi, Vincent Michel, Nicolas Michalski, Pascal Martin
Publicado en: eLife, Edición 8, 2019, Página(s) -, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.43473

Germline MBD4 Mutations and Predisposition to Uveal Melanoma

Autores: Anne-Céline Derrien; Manuel Rodrigues; Manuel Rodrigues; Alexandre Eeckhoutte; Stéphane Dayot; Alexandre Houy; Lenha Mobuchon; Sophie Gardrat; Sophie Gardrat; Delphine Lequin; Stelly Ballet; Gaëlle Pierron; Samar Alsafadi; Samar Alsafadi; Odette Mariani; Ahmed El-Marjou; Alexandre Matet; Alexandre Matet; Chrystelle Colas; Nathalie Cassoux; Nathalie Cassoux; Marc-Henri Stern; Marc-Henri Stern
Publicado en: ournal of the National Cancer Institute, Edición Volume 113, Edición 1, 2021, Página(s) Pages 80–87, ISSN 0027-8874
Editor: Oxford University Press
DOI: 10.1093/jnci/djaa047

Emerging Therapeutic Opportunities Based on Current Knowledge of Uveal Melanoma Biology.

Autores: Vivet-Noguer, Raquel; Tarin, Malcy; Roman-Roman, Sergio; Alsafadi, Samar
Publicado en: Cancers, Edición Iss 7, Vol 11,, 2019, Página(s) p 1019, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11071019

Interpretable network-guided epistasis detection

Autores: Diane Duroux; Héctor Climente-Gonzáles; Chloé-Agathe Azencott; Kristel Van Steen
Publicado en: https://hal-mines-paristech.archives-ouvertes.fr/hal-03114245, Edición 11, 2022, Página(s) 1-14, ISSN 0029-3970
Editor: Oxford University Press
DOI: 10.1093/gigascience/giab093

Spatial transcriptomics for respiratory research and medicine

Autores: Sandra Curras-Alonso, Juliette Soulier, Thomas Walter, Florian Mueller, Arturo Londoño-Vallejo and Charles Fouillade
Publicado en: European Respiratory Journal, Edición 58 (1), 2021, Página(s) 2004314, ISSN 0903-1936
Editor: European Respiratory Society
DOI: 10.1183/13993003.04314-2020

Boosting GWAS using biological networks: A study on susceptibility to familial breast cancer

Autores: Héctor Climente-González; Christine Lonjou; Christine Lonjou; Fabienne Lesueur; Fabienne Lesueur; Dominique Stoppa-Lyonnet; Dominique Stoppa-Lyonnet; Dominique Stoppa-Lyonnet; Nadine Andrieu; Nadine Andrieu; Chloé-Agathe Azencott; Chloé-Agathe Azencott
Publicado en: PLoS Computational Biology, Edición 17(3), 2021, ISSN 1553-734X
Editor: Public Library of Science
DOI: 10.1371/journal.pcbi.1008819

Cortical softening elicits zygotic contractility during mouse preimplantation development

Autores: Özge Özgüç; Ludmilla de Plater; Varun Kapoor; Anna Francesca Tortorelli; Andrew G. Clark; Jean-Léon Maître
Publicado en: PLOS Biology, Edición 20(3), 2022, ISSN 1544-9173
Editor: Public Library of Science
DOI: 10.1371/journal.pbio.3001593

Block HSIC Lasso

Autores: Climente-González, Héctor; Azencott, Chloé Agathe; Kaski, Samuel; Yamada, Makoto
Publicado en: Bioinformatics, Edición Volume 35, issue 14, 2019, ISSN 1367-4803
Editor: Oxford University Press
DOI: 10.1093/bioinformatics/btz333

Melanin Transfer and Fate within Keratinocytes in Human Skin Pigmentation

Autores: Silvia Benito-Martínez, Laura Salavessa, Graça Raposo, Michael S Marks, Cédric Delevoye
Publicado en: Integrative and Comparative Biology, Edición Volume 61, Edición 4, 2021, Página(s) Pages 1546–1555, ISSN 1540-7063
Editor: Oxford University Press
DOI: 10.1093/icb/icab094

Research Techniques Made Simple: Cell Biology Methods for the Analysis of Pigmentation

Autores: Silvia Benito-Martínez, Yueyao Zhu, Riddhi Atul Jani, Dawn C. Harper, Michael S. Marks, Cédric Delevoye
Publicado en: Journal of Investigative Dermatology, Edición Volume 140, Edición 2, 2020, Página(s) 257-268, ISSN 0022-202X
Editor: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.12.002

CARM1/PRMT4: Making Its Mark beyond ItsFunction as a Transcriptional Coactivator

Autores: Samyuktha Suresh, Solène Huard, Thierry Dubois
Publicado en: Trends in Cell Biology, Edición Volume 31, Edición 5, 2021, Página(s) 402-417, ISSN 0962-8924
Editor: Elsevier BV
DOI: 10.1016/j.tcb.2020.12.010

Abstracts

Autores: Mikhajlov
Publicado en: European Biophysics Journal, Edición 46/S1, 2017, Página(s) 43-402, ISSN 0175-7571
Editor: Springer Verlag
DOI: 10.1007/s00249-017-1222-x

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

Autores: Reyka G. Jayasinghe, Song Cao, Qingsong Gao, Michael C. Wendl, Nam Sy Vo, Sheila M. Reynolds, Yanyan Zhao, Héctor Climente-González, Shengjie Chai, Fang Wang, Rajees Varghese, Mo Huang, Wen-Wei Liang, Matthew A. Wyczalkowski, Sohini Sengupta, Zhi Li, Samuel H. Payne, David Fenyö, Jeffrey H. Miner, Matthew J. Walter, Benjamin Vincent, Eduardo Eyras, Ken Chen, Ilya Shmulevich, Feng Chen, Li Ding,
Publicado en: Cell Reports, Edición 23/1, 2018, Página(s) 270-281.e3, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2018.03.052

Harnessing an emissive guanine surrogate to design small-molecule fluorescent chemosensors of O6-methylguanine-DNA-methyltransferase (MGMT)

Autores: Alexandra Fillion,Jaime Franco Pinto, Anton Granzhan
Publicado en: Organic and biomolecular chemistry, Edición 2;20(9), 2022, Página(s) 1888-1892, ISSN 1477-0520
Editor: Royal Society of Chemistry
DOI: 10.1039/d2ob00208f

Preclinical evaluation of drug combinations identifies co-inhibition of Bcl-2/XL/W and MDM2 as a potential therapy in uveal melanoma

Autores: Didier Decaudin, Estelle Frisch Dit Leitz, Fariba Nemati, Malcy Tarin, Adnan Naguez, Mohamed Zerara, Benjamin Marande, Raquel Vivet-Noguer, Ensar Halilovic, Claire Fabre, Aart Jochemsen, Sergio Roman-Roman, Samar Alsafadi
Publicado en: European Journal of Cancer, Edición 126, 2020, Página(s) 93-103, ISSN 0959-8049
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.ejca.2019.12.012

Multiscale analysis of single and double maternal-zygotic Myh9 and Myh10 mutants during mouse preimplantation development.

Autores: Markus Frederik Schliffka; Markus Frederik Schliffka; Anna Francesca Tortorelli; Özge Özgüç; Ludmilla de Plater; Oliver Polzer; Diane Pelzer; Jean-Léon Maître
Publicado en: eLife, 2021, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.68536

Erythropoietin directly remodels the clonal composition of murine hematopoietic multipotent progenitor cells

Autores: Almut S Eisele; Jason Cosgrove; Aurelie Magniez; Emilie Tubeuf; Sabrina Tenreira Bento; Cecile Conrad; Fanny Cayrac; Tamar Tak; Anne-Marie Lyne; Jos Urbanus; Leïla Perié
Publicado en: eLife, 2022, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.66922

The More, the Merrier: DC3s Join the Human Dendritic Cell Family

Autores: Javiera Villar, Elodie Segura
Publicado en: Immunity, Edición Volume 53, Edición 2, 2020, Página(s) 233-235, ISSN 1074-7613
Editor: Cell Press
DOI: 10.1016/j.immuni.2020.07.014

FLASH Irradiation Spares Lung Progenitor Cells and Limits the Incidence of Radio-induced Senescence

Autores: Charles Fouillade, Sandra Curras-Alonso, Lorena Giuranno, Eddy Quelennec, Sophie Heinrich, Sarah Bonnet-Boissinot, Arnaud Beddok, Sophie Leboucher, Hamza Umut Karakurt, Mylène Bohec, Sylvain Baulande, Marc Vooijs, Pierre Verrelle, Marie Dutreix, Arturo Londoño-Vallejo, Vincent Favaudon
Publicado en: Clinical Cancer Research, Edición 15;26(6), 2020, Página(s) 1497-1506, ISSN 1078-0432
Editor: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-19-1440

Roles of Actin in the Morphogenesis of the Early Caenorhabditis elegans Embryo

Autores: Dureen Samandar Eweis; Dureen Samandar Eweis; Julie Plastino; Julie Plastino
Publicado en: International Journal of Molecular Sciences, Edición 21(10), 2020, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21103652

Developing an advanced gut on chip model enabling the study of epithelial cell/fibroblast interactions

Autores: Marine Verhulsel, Anthony Simon, Moencopi Bernheim-Dennery, Venkata Ram Gannavarapu, Lauriane Gérémie, Davide Ferraro, Denis Krndija, Laurence Talini, Jean-Louis Viovy, Danijela Matic Vignjevic, Stéphanie Descroix
Publicado en: Lab Chip, Edición 21, 2021, Página(s) 365, ISSN 1473-0197
Editor: Royal Society of Chemistry
DOI: 10.1039/d0lc00672f

An interhemispheric neural circuit allowing binocular integration in the optic tectum.

Autores: Gebhardt, Christoph; Auer, Thomas O.; Henriques, Pedro M.; Rajan, Gokul; Duroure, Karine; Bianco, Isaac H.; Del Bene, Filippo
Publicado en: Nature Communications, Edición 10, 2019, Página(s) 5471, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-019-13484-9

Decoding the Heterogeneity of Human Dendritic Cell Subsets

Autores: Javiera Villar; Elodie Segura
Publicado en: Trends in Inmunology, Edición Volume 41, Edición 12, 2020, Página(s) Pages 1062-107, ISSN 1471-4906
Editor: Elsevier BV
DOI: 10.1016/j.it.2020.10.002

Spen limits intestinal stem cell self-renewal

Autores: Maheva Andriatsilavo, Marine Stefanutti, Katarzyna Siudeja, Carolina N Perdigoto, Benjamin Boumard, Louis Gervais, Alexandre Gillet-Markowska, Lara Al Zouabi, François Schweisguth, Allison J Bardin
Publicado en: PLOS Genetics, Edición 14(11), 2018, Página(s) -, ISSN 1553-7390
Editor: Public Library of Science
DOI: 10.1371/journal.pgen.1007773

Evolutionary divergence of locomotion in two related vertebrate species

Autores: Gokul Rajan; Julie Lafaye; Martin Carbo-Tano; Karine Duroure; Giulia Faini; Dimitrii Tanese; Thomas Panier; Raphaël Candelier; Joerg Henninger; Ralf Britz; Benjamin Judkewitz; Christoph Gebhardt; Valentina Emiliani; Georges Debrégeas; Claire Wyart; Filippo Del Bene
Publicado en: Cell Reports, Edición Volume 38, Edición 13, 2022, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2022.110585

TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer.

Autores: Florent Dufour; Florent Dufour; Linda Silina; Linda Silina; Hélène Neyret-Kahn; Hélène Neyret-Kahn; Aura Moreno-Vega; Aura Moreno-Vega; Clémentine Krucker; Clémentine Krucker; Narjesse Karboul; Narjesse Karboul; Marion Dorland-Galliot; Marion Dorland-Galliot; Pascale Maillé; Elodie Chapeaublanc; Elodie Chapeaublanc; Yves Allory; Yves Allory; Nicolas Stransky; Nicolas Stransky; Hélène Haeg
Publicado en: British Journal of Cancer, Edición 120 (5), 2019, Página(s) pp.555-564, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41416-019-0397-6

Protein arginine methyltransferase 5: A novel therapeutic target for triple-negative breast cancers

Autores: Mathilde Vinet, Samyuktha Suresh, Virginie Maire, Clarisse Monchecourt, Fariba Némati, Laetitia Lesage, Fabienne Pierre, Mengliang Ye, Auriane Lescure, Amélie Brisson, Didier Meseure, André Nicolas, Guillem Rigaill, Elisabetta Marangoni, Elaine Del Nery, Sergio Roman‐Roman, and Thierry Dubois
Publicado en: Cancer Medicine, Edición Volume 8, Edición 5, 2019, Página(s) 2414–2428, ISSN 2045-7634
Editor: John Wiley & Sons
DOI: 10.1002/cam4.2114

Asymmetry is defined during meiosis in the oocyte of the parthenogenetic nematode Diploscapter pachys

Autores: Dureen Samandar Eweis; Marie Delattre; Julie Plastino
Publicado en: Developmental Biology, Edición 00121606, 2022, Página(s) Pages 13-21, ISSN 0012-1606
Editor: Academic Press
DOI: 10.1016/j.ydbio.2021.12.013

Controlling Confinement and Topology to Study Collective Cell Behaviors

Autores: Guillaume Duclos, Maxime Deforet, Hannah G. Yevick, Olivier Cochet-Escartin, Flora Ascione, Sarah Moitrier, Trinish Sarkar, Victor Yashunsky, Isabelle Bonnet, Axel Buguin, Pascal Silberzan
Publicado en: Cell Migration. Methods in Molecular Biology, Edición vol 1749, 2018, Página(s) pp 387–399, ISBN 978-1-4939-7700-0
Editor: Humana Press
DOI: 10.1007/978-1-4939-7701-7_28

The 2020 motile active matter roadmap

Autores: Gerhard Gompper, Roland G Winkler, Thomas Speck, Alexandre Solon, Cesare Nardini, Fernando Peruani, Hartmut Löwen, Ramin Golestanian, U Benjamin Kaupp, Luis Alvarez, Thomas Kiørboe, Eric Lauga, Wilson C K Poon, Antonio DeSimone, Santiago Muiños-Landin, Alexander Fischer, Nicola A Söker, Frank Cichos, Raymond Kapral, Pierre Gaspard, Marisol Ripoll, Francesc Sagues, Amin Doostmohammadi, Julia M
Publicado en: Journal of Physics: Condensed Matter, Edición 193001, 2020, Página(s) 67pp, ISSN 0953-8984
Editor: IOP Publishing
DOI: 10.1088/1361-648x/ab6348

The 2019 Motile Active Matter Roadmap

Autores: Gompper, Gerhard; Winkler, Roland G.; Speck, Thomas; Solon, Alexandre; Nardini, Cesare; Peruani, Fernando; Loewen, Hartmut; Golestanian, Ramin; Kaupp, U. Benjamin; Alvarez, Luis; Kioerboe, Thomas; Lauga, Eric; Poon, Wilson; De Simone, Antonio; Cichos, Frank; Fischer, Alexander; Landin, Santiago Muinos; Soeker, Nicola; Kapral, Raymond; Gaspard, Pierre; Ripoll, Marisol; Sagues, Francesc; Yeomans, Ju
Publicado en: arXiv, 2019, ISSN 2331-8422
Editor: Cornell University
DOI: 10.48550/arxiv.1912.06710

Genome-wide mapping of human DNA replication by optical replication mapping supports a stochastic model of eukaryotic replication

Autores: Wang W, Klein KN, Proesmans K, Yang H, Marchal C, Zhu X, Borrman T, Hastie A, Weng Z, Bechhoefer J, Chen CL, Gilbert DM, Rhind N.
Publicado en: Mol Cell, Edición Jul 15;81(14), 2021, Página(s) 2975-2988, ISSN 1940-3402
Editor: Cold Spring Harbor Laboratory
DOI: 10.1016/j.molcel.2021.05.024

Real Time de novo Deposition of Centromeric Histone-associated Proteins Using the Auxin Inducible Degradation System

Autores: Hoffmann, Sebastian; Fachinetti, Daniele
Publicado en: Histone Variants. Methods in Molecular Biology, Edición vol 1832, 2018, ISBN 978-1-4939-8663-7
Editor: Humana Press
DOI: 10.1007/978-1-4939-8663-7_12

Derechos de propiedad intelectual

METALLIC TRANS-(N-HETEROCYCLIC CARBENE)-AMINE-PLATINUM COMPLEXES AND USES THEREOF FOR TREATING CANCER

Número de solicitud/publicación: 20 21078966
Fecha: 2021-10-19
Solicitante(s): INSTITUT CURIE

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Publicaciones

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