Deliverables Documents, reports (12) Physiology of normal and cystic fibrosis bronchial epithelium; Imaging assay Physiology of normal and cystic fibrosis bronchial epithelium; Imaging assay pH-insensitive Cl- sensor assay iPS cells from G551D patients Lung epithelial cells from F508del patients iPS cells from F508del patients Correlation of anion transport activity with mucin release in Calu-3 CFTR wt and mutant sensor cell lines Calu-3 mutant CFTR F508del and G551D cells Intestinal organoids from G551D patients Anionophores in F508del and G551D mouse models Lung epithelial cells from G551D patients Biophysical and pharmacological characterisation of the anionophores Intestinal organoids from F508del patients Websites, patent fillings, videos etc. (1) Project Website Publications Peer reviewed articles (3) Anion-Transport Mechanism of a Triazole-Bearing Derivative of Prodigiosine: A Candidate for Cystic Fibrosis Therapy Author(s): Claudia Cossu, Michele Fiore, Debora Baroni, Valeria Capurro, Emanuela Caci, Maria Garcia-Valverde, Roberto Quesada, Oscar Moran Published in: Frontiers in Pharmacology, Issue 9, 2018, ISSN 1663-9812 Publisher: Frontiers Media S.A. DOI: 10.3389/fphar.2018.00852 Small molecule anionophores promote transmembrane anion permeation matching CFTR activity Author(s): Elsa Hernando, Valeria Capurro, Claudia Cossu, Michele Fiore, María García-Valverde, Vanessa Soto-Cerrato, Ricardo Pérez-Tomás, Oscar Moran, Olga Zegarra-Moran, Roberto Quesada Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-018-20708-3 Generation of two induced pluripotent stem cell (iPSC) lines from p.F508del Cystic Fibrosis patients Author(s): Aarne Fleischer, Iván M. Lorenzo, Esther Palomino, Trond Aasen, Fernando Gómez, Miguel Servera, Víctor J. Asensio, Víctor Gálvez, Juan Carlos Izpisúa-Belmonte, Daniel Bachiller Published in: Stem Cell Research, Issue 29, 2018, Page(s) 1-5, ISSN 1873-5061 Publisher: Elsevier DOI: 10.1016/j.scr.2018.03.004 Other (6) 5th TAT-CF Newsletter Author(s): Ángel del Pozo, Roberto Quesada Published in: 2018 Publisher: TAT-CF consortium 3rd TAT-CF Newsletter Author(s): Ángel del Pozo, Roberto Quesada, Oscar Moran, Emanuela Caci Published in: 2018 Publisher: TAT-CF consortium 4th TAT-CF Newsletter Author(s): Ángel del Pozo, Roberto Quesada, Manfred Frey Published in: 2018 Publisher: TAT-CF consortium 6th TAT-CF Newsletter Author(s): Ángel del Pozo, Roberto Quesada, Oscar Moran, Emanuela Caci, Manfred Frey, Daniel Bachiller, Anette Mullertz, Laszlo Puskas Published in: 2018 Publisher: TAT-CF consortium 1st TAT-CF Newsletter Author(s): Ángel del Pozo, Roberto Quesada Published in: 2016 Publisher: TAT-CF consortium 2nd TAT-CF Newsletter Author(s): Ángel del Pozo, Daniel Bachiller, Oscar Moran, Roberto Quesada Published in: 2017 Publisher: TAT-CF consortium Conference proceedings (9) Biologically Active Transmembrane Anion Transporters Author(s): Roberto Quesada, Elsa Hernando, Francisco Ciruela, Vanesa Soto-Cerrato, Ricardo Pérez-Tomás, and Rosa Farràs. Published in: Abstract book of the III Biennial Meeting of the Chemical Biology Group / XII Carbohydrate Symposium, 2016 Publisher: Royal Society of Chemistry of Spain (RSEQ) Phospholipids vesicles as convenient models to study transmembrane ion transport Author(s): Sandra Díaz, Elsa Hernando and Roberto Quesada Published in: Abstract book of the 6th Early Stage Researchers Workshop in Nanoscience, 2016 Publisher: Instituto IMDEA nanociencia Bromination of 2, 7' bi-indolyls and quinazolin-7-ones as a key step in the synthesis of macrocyclic tetra-indolyls Author(s): Marcin Mielczarek, Mohan Bhadbhade, Rui Chen, Naresh Kumar, David St. C. Black Published in: Abstract book of the 3rd ERC Grantees Conference, 2016 Publisher: University of Groningen An UGI/Intramolecular cyclization sequence for the synthesis of nitrogen-based heterocycles Author(s): Pablo Peña-Calleja, Pablo Pertejo, Roberto Quesada, María García-Valverde Published in: Abstract book of the 17th Tetrahedron Symposium, 2016 Publisher: Elsevier New transmembrane anion transporters based on tetraheterocycle structures Author(s): Israel Carreira-Barral, Elsa Hernando, Roberto Quesada. Published in: Abstract book of the 6th EuCheMS Chemistry Congress, 2016 Publisher: The National Chemists Association of Spain (ANQUE) Directed differentiation and genetic modification of novel iPS cell lines from CF patients Author(s): Daniel Bachiller, Aarne Fleischer, Esther Palomino, Ivan Lorenzo, Victor Galvez, Trond Aasen, Juan Carlos Izpisua-Belmonte, Fernando Gomez Published in: Abstract book of the ECFS Basic Science Conference 2017, 2017 Publisher: European Cystic Fibrosis Society TAT:CF: Novel therapeutic approaches for the treatment of cystic fibrosis based on small molecule transmembrane anion transporters through open innovation Author(s): Angel del Pozo, Marta Pastor, Roberto Quesada, Yolanda Gil, TAT-CF Consortium Published in: Abstract book of the the 3rd International Rare Diseases Research Consortium (IRDiRC) Conference, 2017 Publisher: International Rare Diseases Research Consortium Facilitated transmembrane transport, a viable therapeutic approach for channelopathies? Author(s): Roberto Quesada, Israel Carreira, Marcin Mielczarek, María García-Valverde, Olga Zegarra, Oscar Morán, Angel del Pozo, Laszlo Puskas, Anette Mullertz, Manfred Fey and Daniel Bachiller Published in: Abstract book of the 3rd International Rare Diseases Research Consortium (IRDiRC) Conference, 2017 Publisher: International Rare Diseases Research Consortium Anion transport mechanisms through lipid bilayers by synthetic ionophores: towards a cystic fibrosis therapy Author(s): Claudia Cossu, Michele Fiore, Olga Zegarra-Moran, Valeria Capurro, Elsa Henando, Roberto Quesada and Oscar Moran Published in: Abstract book for the XXIII Congresso Nazionale Società Italiana di Biofisica Pura e Applicata, 2016 Publisher: Società Italiana di Biofisica Pura e Applicata Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
