Matrix during cancer progression

Información del proyecto

MATRICAN

Identificador del acuerdo de subvención: 682881

DOI 10.3030/682881

Proyecto cerrado

Fecha de la firma de la CE 8 Agosto 2016

Fecha de inicio 1 Septiembre 2016

Fecha de finalización 31 Agosto 2021

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total € 1 997 500,00

Aportación de la UE € 1 997 500,00

Coordinado por

KOBENHAVNS UNIVERSITET
Denmark

Publicaciones

Peer reviewed articles (7)

Deciphering the temporal heterogeneity of cancer-associated fibroblast subpopulations in breast cancer

Autores: Freja Albjerg Venning, Kamilla Westarp Zornhagen, Lena Wullkopf, Jonas Sjölund, Carmen Rodriguez-Cupello, Pontus Kjellman, Mikkel Morsing, Morteza Chalabi Hajkarim, Kyoung Jae Won, Janine Terra Erler, Chris Denis Madsen
Publicado en: Journal of Experimental & Clinical Cancer Research, Edición 40/1, 2021, ISSN 1756-9966
Editor: Springer Nature
DOI: 10.1186/s13046-021-01944-4

Organ-Specific, Fibroblast-Derived Matrix as a Tool for Studying Breast Cancer Metastasis

Autores: Adina R. D. Jensen, Edward R. Horton, Lene H. Blicher, Elin J. Pietras, Cornelia Steinhauer, Raphael Reuten, Erwin M. Schoof, Janine T. Erler
Publicado en: Cancers, Edición 13/13, 2021, Página(s) 3331, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13133331

Basement membrane stiffness determines metastases formation

Autores: Raphael Reuten, Sina Zendehroud, Monica Nicolau, Lutz Fleischhauer, Anu Laitala, Stefanie Kiderlen, Denise Nikodemus, Lena Wullkopf, Sebastian Rune Nielsen, Sarah McNeilly, Carina Prein, Maria Rafaeva, Erwin M. Schoof, Benjamin Furtwängler, Bo T. Porse, Hyobin Kim, Kyoung Jae Won, Stefanie Sudhop, Kamilla Westarp Zornhagen, Frank Suhr, Eleni Maniati, Oliver M. T. Pearce, Manuel Koch, Lene Broeng
Publicado en: Nature Materials, 2021, ISSN 1476-1122
Editor: Nature Publishing Group
DOI: 10.1038/s41563-020-00894-0

Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade

Autores: Sebastian R. Nielsen, Jan E. Strøbech, Edward R. Horton, Rene Jackstadt, Anu Laitala, Marina C. Bravo, Giorgia Maltese, Adina R. D. Jensen, Raphael Reuten, Maria Rafaeva, Saadia A. Karim, Chang-Il Hwang, Luis Arnes, David A. Tuveson, Owen J. Sansom, Jennifer P. Morton, Janine T. Erler
Publicado en: Nature Communications, Edición 12/1, 2021, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-23731-7

ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix

Autores: Alejandro E Mayorca-Guiliani, Chris D Madsen, Thomas R Cox, Edward R Horton, Freja A Venning, Janine T Erler
Publicado en: Nature Medicine, Edición 23/7, 2017, Página(s) 890-898, ISSN 1078-8956
Editor: Nature Publishing Group
DOI: 10.1038/nm.4352

Mesenchymal stromal cell activation by breast cancer secretomes in bioengineered 3D microenvironments

Autores: Ulrich Blache, Edward R Horton, Tian Xia, Erwin M Schoof, Lene H Blicher, Angelina Schönenberger, Jess G Snedeker, Ivan Martin, Janine T Erler, Martin Ehrbar
Publicado en: Life Science Alliance, Edición 2/3, 2019, Página(s) e201900304, ISSN 2575-1077
Editor: Life Science Alliance
DOI: 10.26508/lsa.201900304

Decellularization and antibody staining of mouse tissues to map native extracellular matrix structures in 3D

Autores: Alejandro E Mayorca-Guiliani, Oliver Willacy, Chris D. Madsen, Maria Rafaeva, Stefanie Elisabeth Heumüller, Felix Bock, Gerhard Sengle, Manuel Koch, Thomas Imhof, Frank Zaucke, Raimund Wagener, Takako Sasaki, Janine T. Erler, Raphael Reuten
Publicado en: Nature Protocols, 2019, ISSN 1754-2189
Editor: Nature Publishing Group
DOI: 10.1038/s41596-019-0225-8