Descrizione del progetto
Interferenti endocrini nei prodotti di uso quotidiano
Gli interferenti endocrini si trovano in una serie di prodotti di uso quotidiano, dai cosmetici ai pesticidi e agli imballaggi alimentari. Permeano i prodotti di uso quotidiano e rappresentano una grave minaccia per la nostra salute e per l’ambiente. È un problema che contribuisce al fallimento dei sistemi ecologici, alla scarsa produzione agricola e a problemi di salute come obesità, cancro e infertilità. Sebbene i metodi analitici siano avanzati, l’attenzione si è concentrata principalmente sulle sostanze chimiche di sintesi, ignorando gli interferenti endocrini emergenti e l’esposizione reale a più sostanze. Il progetto PROTECTED, finanziato dall’UE, mira a sviluppare capacità di protezione contro queste sostanze. Andrà oltre la ricerca e lo sviluppo, fornendo ai suoi partecipanti una formazione unica e di alto livello. In ultima analisi, tali specialisti assumeranno la guida nel definire le future strategie di controllo e nel migliorare gli esiti sanitari.
Obiettivo
PROTECTED aims to develop expertise and protective capabilities against Endocrine Disruptors (EDs). EDs and their mixtures are a modern day health concern leading to failing ecological systems, poor agricultural production and health effects such as obesity, cancer and infertility. While analytical methods have advanced enormously, focus has been mainly on synthetic chemicals, overlooking emerging EDs and real-life multiple substance exposure. A new generation of creative, entrepreneurial and innovative early-stage researchers equipped with skills to assess and understand the real-life risk of complex mixtures of EDs and trained to convert resulting knowledge and ideas into accessible tools and services for the long-term control of potential ED risk is urgently needed. The PROTECTED Innovative Training Network [ITN] proposes a holistic approach by providing 15 individual, personalised research projects with exposure to scientific, innovative and entrepreneurial training mobility across the ITN. The intersectorial network is comprised of 12 training sites at academia, research centres, a bioassay technology SME, a QSAR technology SME, water provider, and animal feed supplier. Together they cover multiple disciplines including analytical science of food, feed, and environment, epidemiology, risk assessment, social science and toxicology. This combined expertise enables a highly focused program for developing novel tools and concepts and training for the detection, analysis and improved risk assessment of EDs, especially mixture effects. Methodology will include emerging technologies; multiplexed analysis, mixture modelling, mechanistic and exposure studies, explants and cell or whole organism bioassays. The project will provide a unique and high level of training for a new generation of specialists with transferable skills and enhanced career perspectives. These specialists will ultimately aid the efficient development of future control strategies for improved health.
Campo scientifico
- medical and health scienceshealth sciencespublic healthepidemiology
- medical and health sciencesclinical medicineoncology
- medical and health sciencesbasic medicinetoxicology
- medical and health scienceshealth sciencesnutritionobesity
- agricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandryanimal feed
Programma(i)
Argomento(i)
Meccanismo di finanziamento
MSCA-ITN-ETN - European Training NetworksCoordinatore
BT7 1NN Belfast
Regno Unito