Safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS)

Información del proyecto

TUDCA-ALS

Identificador del acuerdo de subvención: 755094

DOI 10.3030/755094

Proyecto cerrado

Fecha de la firma de la CE 15 Noviembre 2017

Fecha de inicio 1 Enero 2018

Fecha de finalización 31 Diciembre 2023

Financiado con arreglo a

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Coste total € 5 596 928,00

Aportación de la UE € 5 596 928,00

Coordinado por

HUMANITAS MIRASOLE SPA
Italy

Resultado final

Documents, reports (1)

Dissemination and exploitation plan

Dissemination and Exploitation Plan. The document will describe the dissemination and exploitation strategies and action plan (Month 3

Websites, patent fillings, videos etc. (1)

Project website

Project website. The report will include the characteristics of the website, the activities involved for its creation and print screens of the website pages (Month 6

Publicaciones

Peer reviewed articles (6)

Review of disease-modifying drug trials in amyotrophic lateral sclerosis

Autores: Paolo Tornese; Stefania Lalli; Antoniangela Cocco; Alberto Albanese
Publicado en: Journal of Neurology Neurosurgery and Psychiatry, Edición 3, 2022, Página(s) 521-529, ISSN 0022-3050
Editor: BMJ Publishing Group
DOI: 10.1136/jnnp-2021-328470

Tauro-Urso-Deoxycholic Acid Trials in Amyotrophic Lateral Sclerosis: What is Achieved and What to Expect

Autores: Maria Lo Giudice, Antoniangela Cocco, Giorgio Reggiardo, Stefania Lalli, Alberto Albanese
Publicado en: Clinical Drug Investigation, 2023, ISSN 1179-1918
Editor: Springer
DOI: 10.1007/s40261-023-01324-0

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases

Autores: Kareem Khalaf; Paolo Tornese; Antoniangela Cocco; Alberto Albanese
Publicado en: Translational Neurodegeneration, Edición 3, 2022, Página(s) 33, ISSN 2047-9158
Editor: Springer Nature
DOI: 10.1186/s40035-022-00307-z

A randomized double-blind clinical trial on safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS): the statistical analysis plan of TUDCA-ALS trial

Autores: Flavia L Lombardo, Stefania Spila Alegiani, Flavia Mayer, Marta Cipriani, Maria Lo Giudice, Albert Christian Ludolph, Christopher J McDermott, Philippe Corcia, Philip Van Damme, Leonard H Van den Berg, Orla Hardiman, Gabriele Nicolini, Nicola Vanacore, Brian Dickie, Alberto Albanese, Maria Puopolo; TUDCA-ALS Study Group (Paolo Tornese, Antoniangela Cocco, Michela Matteoli, Eliana Lauranzano, Maria
Publicado en: Trials, 2023, ISSN 1745-6215
Editor: BioMed Central
DOI: 10.1186/s13063-023-07638-w

Cox regression and survival analysis from the tauro-urso-deoxycholic trial in amyotrophic lateral sclerosis

Autores: Giorgio Reggiardo; Maria Lo Giudice; Stefania Lalli; Gilberto Rinaldi; Alberto Albanese
Publicado en: Frontiers in Neurology, Edición 5, 2023, ISSN 1664-2295
Editor: Frontiers Research Foundation
DOI: 10.3389/fneur.2023.1163855

Tauroursodeoxycholic acid in patients with amyotrophic lateral sclerosis: The TUDCA-ALS trial protocol

Autores: Alberto Albanese, Albert Christian Ludolph, Christopher J McDermott, Philippe Corcia, Philip Van Damme, Leonard H Van den Berg, Orla Hardiman, Gilberto Rinaldi, Nicola Vanacore, Brian Dickie, TUDCA-ALS Study Group (Tornese Paolo, Cocco Antoniangela, Lo Giudice Maria, Matteoli Michela, Lauranzano Eliana, Malosio Maria Luisa, Adriana Elia Chiara, Lombardo Flavia, Mayer Flavia, Puopolo Maria, Alegian
Publicado en: Frontiers in Neurology, Edición 16642295, 2022, ISSN 1664-2295
Editor: Frontiers Research Foundation
DOI: 10.3389/fneur.2022.1009113