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CORDIS - Resultados de investigaciones de la UE
CORDIS

Safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS)

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Report on status of posting results in the study registry (se abrirá en una nueva ventana)

Report on status of posting results in the study registry. The report will include the status of the result posting as well as the timelines when final posting of results is scheduled at end of funding period (Month 72)

Dissemination and exploitation plan (se abrirá en una nueva ventana)

Dissemination and Exploitation Plan. The document will describe the dissemination and exploitation strategies and action plan (Month 3

Statistical analysis of primary and secondary outcome variables (se abrirá en una nueva ventana)

Statistical analysis of primary and secondary outcome variables. (Month 72) This report will include the statistical analysis on primary and secondaty outcome variables

Demographic and clinical description of the study population (se abrirá en una nueva ventana)

This report will include study population data on demographic and clinical aspects

Statistical analysis of biomarker and correlation with clinical outcomes (se abrirá en una nueva ventana)

Statistical analysis of biomarker and correlation with clinical outcomes. (Month 66) This report will include data on statistical analysis of biomarkers and related correlation to clinical outcomes.

Project website (se abrirá en una nueva ventana)

Project website. The report will include the characteristics of the website, the activities involved for its creation and print screens of the website pages (Month 6

Publicaciones

Review of disease-modifying drug trials in amyotrophic lateral sclerosis (se abrirá en una nueva ventana)

Autores: Paolo Tornese; Stefania Lalli; Antoniangela Cocco; Alberto Albanese
Publicado en: Journal of Neurology Neurosurgery and Psychiatry, Edición 3, 2022, Página(s) 521-529, ISSN 0022-3050
Editor: BMJ Publishing Group
DOI: 10.1136/jnnp-2021-328470

Tauro-Urso-Deoxycholic Acid Trials in Amyotrophic Lateral Sclerosis: What is Achieved and What to Expect (se abrirá en una nueva ventana)

Autores: Maria Lo Giudice, Antoniangela Cocco, Giorgio Reggiardo, Stefania Lalli, Alberto Albanese
Publicado en: Clinical Drug Investigation, 2023, ISSN 1179-1918
Editor: Springer
DOI: 10.1007/s40261-023-01324-0

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases (se abrirá en una nueva ventana)

Autores: Kareem Khalaf; Paolo Tornese; Antoniangela Cocco; Alberto Albanese
Publicado en: Translational Neurodegeneration, Edición 3, 2022, Página(s) 33, ISSN 2047-9158
Editor: Springer Nature
DOI: 10.1186/s40035-022-00307-z

A randomized double-blind clinical trial on safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS): the statistical analysis plan of TUDCA-ALS trial (se abrirá en una nueva ventana)

Autores: Flavia L Lombardo, Stefania Spila Alegiani, Flavia Mayer, Marta Cipriani, Maria Lo Giudice, Albert Christian Ludolph, Christopher J McDermott, Philippe Corcia, Philip Van Damme, Leonard H Van den Berg, Orla Hardiman, Gabriele Nicolini, Nicola Vanacore, Brian Dickie, Alberto Albanese, Maria Puopolo; TUDCA-ALS Study Group (Paolo Tornese, Antoniangela Cocco, Michela Matteoli, Eliana Lauranzano, Maria
Publicado en: Trials, 2023, ISSN 1745-6215
Editor: BioMed Central
DOI: 10.1186/s13063-023-07638-w

Cox regression and survival analysis from the tauro-urso-deoxycholic trial in amyotrophic lateral sclerosis (se abrirá en una nueva ventana)

Autores: Giorgio Reggiardo; Maria Lo Giudice; Stefania Lalli; Gilberto Rinaldi; Alberto Albanese
Publicado en: Frontiers in Neurology, Edición 5, 2023, ISSN 1664-2295
Editor: Frontiers Research Foundation
DOI: 10.3389/fneur.2023.1163855

Tauroursodeoxycholic acid in patients with amyotrophic lateral sclerosis: The TUDCA-ALS trial protocol (se abrirá en una nueva ventana)

Autores: Alberto Albanese, Albert Christian Ludolph, Christopher J McDermott, Philippe Corcia, Philip Van Damme, Leonard H Van den Berg, Orla Hardiman, Gilberto Rinaldi, Nicola Vanacore, Brian Dickie, TUDCA-ALS Study Group (Tornese Paolo, Cocco Antoniangela, Lo Giudice Maria, Matteoli Michela, Lauranzano Eliana, Malosio Maria Luisa, Adriana Elia Chiara, Lombardo Flavia, Mayer Flavia, Puopolo Maria, Alegian
Publicado en: Frontiers in Neurology, Edición 16642295, 2022, ISSN 1664-2295
Editor: Frontiers Research Foundation
DOI: 10.3389/fneur.2022.1009113

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