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CORDIS

The Developmental Origins of Health: Biology, Shocks, Investments, and Policies

Projektbeschreibung

Auseinandersetzung mit den Ursachen für gesundheitliche Ungleichheit

Gesundheitliche Ungleichheit hat ihren Ursprung in vielen unterschiedlichen Umgebungen, Bedingungen und Erschütterungen in der Kindheit. Unser Verständnis der entwicklungsbedingten Ursprünge von Ungleichheiten im frühen Kindesalter ist nach wie vor beschränkt. Fest steht, dass es dringend notwendig ist, präventive Gesundheitspolitik und Interventionen zu entwickeln, die eine gerechte, gesunde Zukunft für unsere Gesellschaften ermöglichen. Das EU-finanzierte Projekt DEVORHBIOSHIP wird das Zusammenspiel von Genen und Umgebung in verschiedenen Entwicklungsstadien untersuchen. Verwendet wird dabei eine Kombination aus qualitativ hochwertigen Daten, sensiblen Messwerten und robusten Identifikationsstrategien sowie ökonometrischen Methoden für Beobachtungsdaten und experimentelle Daten. Die Ergebnisse werden direkte Auswirkungen auf die Gestaltung neuer kostengünstiger, gesundheitsfördernder Interventionen haben.

Ziel

What are the origins of inequalities in health? A recent literature in economics has established causal impacts of early life shocks, investments and policies on lifelong health. However, several unknowns remain. The mechanisms through which shocks, investments, and policies interact are just beginning to be understood. Our knowledge of sensitive periods is imprecise. Little is also known about the impact of shocks and policies across different ages. Commonly used health capital measures, such as birth weight, lack sensitivity and specificity. The interplay between genes and environments in the formation of health inequalities is poorly understood.
To fill these gaps, I will build on insights from my earlier work, and use a combination of high-quality data, more sensitive measures, robust identification strategies and richer models to untangle the complex interactions between biology, shocks, investments and policies.
First, I will investigate causal impacts and mechanisms of two public health policies on child health and development: medical treatments for pregnancy complications and prenatal home visiting programmes. Second, I will examine the effects of two environmental shocks (pollution and influenza) on the formation of early health and human capital, and their interplay with maternal investments in nutrition. Third, I will study interactions between shocks, investments and policies from birth to adulthood, to understand the dynamic interplay between SES and health. Throughout, I will explore their interactions with genetic susceptibility or potential.
I will analyse administrative records, registries linked to survey data, cohort data with biomarkers; and a randomized controlled trial. I will use state-of-the-art econometric techniques for observational and experimental data. My findings will have direct policy implications and will help understand whether and to which extent early life interventions are a cost-effective mean to promote health.

Gastgebende Einrichtung

UNIVERSITY COLLEGE LONDON
Netto-EU-Beitrag
€ 1 713 798,00
Adresse
GOWER STREET
WC1E 6BT London
Vereinigtes Königreich

Auf der Karte ansehen

Region
London Inner London — West Camden and City of London
Aktivitätstyp
Higher or Secondary Education Establishments
Links
Gesamtkosten
€ 1 713 798,00

Begünstigte (2)