Objective
I propose to generate a PDK1 knocking mouse embryonic stem cell line that expresses a mutated form of DKP1 which PH-domain can not interact with PtdIns (3,4,5)P3. The study of this cell line will permit to further understand the mechanism by which PtdIns(3,4,5)P_3 regulates the insulin signal transduction
Topic(s)
Data not availableCall for proposal
Data not availableFunding Scheme
RGI - Research grants (individual fellowships)Coordinator
DD1 4HN DUNDEE
United Kingdom