Objective I propose to analyse the genetic program that controls the development of human helper T cell subsets on a genome-wide scale using microarrays. In particular, I will define the regulation of T-bet and GATA-3 transcription factors and their role in the initiation of The- or The-specific transcriptional cascades. Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-2. - Key action Control of Infectious Diseases Call for proposal Data not available Funding Scheme RGI - Research grants (individual fellowships) Coordinator INSTITUT PASTEUR EU contribution No data Address Rue du Docteur Roux 25 75724 PARIS France See on map Total cost No data