Cel Organocopper reagents are of importance in organic synthesis because of their versatile reactivity pattern including cross coupling and 1,4-conjugate addition as well as SN2 and SN2' displacement reactions. Their use has made available an overwhelming number of new, and often very short, synthetic pathways to valuable molecules like prostanoids, pheromones, antitumour compounds and fragrance compounds.As many of these target molecules are chiral, a direct need for control of the absolute configuration in their synthesis emerged for environmental and biological reasons. It is this aspect that has been addressed in the present work.Novel types of ortho-functionalised arylcopper compounds were synthesised and structurally characterised. A new chiral arenethiolatecopper(I) compound was synthesised, which appeared to be a promising catalyst (9 mole %) for the enantioselective 1,4-addition of methylmagnesium halide to benzylideneacetone. Unprecedented selective exchange reactions between organolithium, organocopper and organomagnesium reagents and arenethiolatecopper(I) compounds have been established and structurally characterised. Dziedzina nauki natural scienceschemical sciencescatalysis Program(-y) FP1-STIMULATION 1C - Plan (EEC) to stimulate European scientific and technical cooperation and interchange, 1985-1988 Temat(-y) Data not available Zaproszenie do składania wniosków Data not available System finansowania CSC - Cost-sharing contracts Koordynator WISE & MUNRO LEARNING RESEARCH Wkład UE Brak danych Adres 8,Azaleastraat 85 2565 CD DEN HAAG Niderlandy Zobacz na mapie Linki Strona internetowa Opens in new window Koszt całkowity Brak danych Uczestnicy (1) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko UNIVERSITE LOUIS PASTEUR, STRASBOURG 1 Francja Wkład UE Brak danych Adres Rue Blaise Pascal 4 67070 STRASBOURG Zobacz na mapie Koszt całkowity Brak danych
