Objetivo I propose to generate a PDK1 knocking mouse embryonic stem cell line that expresses a mutated form of DKP1 which PH-domain can not interact with PtdIns (3,4,5)P3. The study of this cell line will permit to further understand the mechanism by which PtdIns(3,4,5)P_3 regulates the insulin signal transduction Ámbito científico medical and health sciencesmedical biotechnologycells technologiesstem cells Programa(s) FP5-HUMAN POTENTIAL - Programme for research, technological development and demonstration on "Improving the human research potential and the socio-economic knowledge base" (1998-2002) Tema(s) Data not available Convocatoria de propuestas Data not available Régimen de financiación RGI - Research grants (individual fellowships) Coordinador UNIVERSITY OF DUNDEE Aportación de la UE Sin datos Dirección Nethergate DD1 4HN DUNDEE Reino Unido Ver en el mapa Coste total Sin datos
